Guillain-Barré syndrome natural history, complications, and prognosis
Guillain-Barré syndrome Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Guillain-Barré syndrome natural history, complications, and prognosis On the Web |
American Roentgen Ray Society Images of Guillain-Barré syndrome natural history, complications, and prognosis |
FDA on Guillain-Barré syndrome natural history, complications, and prognosis |
CDC on Guillain-Barré syndrome natural history, complications, and prognosis |
Guillain-Barré syndrome natural history, complications, and prognosis in the news |
Blogs on Guillain-Barré syndrome natural history, complications, and prognosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Fahimeh Shojaei, M.D.
Overview
Approximately 80% of patients have a complete recovery within a few months to a year, although minor findings may persist. A patient's outcome is most likely to be very good when the symptoms go away within 3 weeks after they first started. Complications like paralysis, respiratory failure and hypotension can be seen in these patients.
Natural History, Complications, and Prognosis
Natural history
- The symptoms of Guillain Barre syndrome typically develop 1 to 3 weeks after the Antecedent Infection.
- If left untreated, 65% of patients with Guillain Barre syndrome will recover with may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. GBS has a different natural history in every patient based on age and the speed of symptoms occurrence, so it can lead to death or patients may fully recover no matter what the etiology is.[1][2]
Complications
- Common complications of GBS include:[3][4]
- respiratory failure
- Autonomic failure
- Bulbar pulsy
- Deep vein thrombosis
- Cardiac arrhythmia
- Pain
- Urinary retention
- Ileus
- Persistent fatigue
Prognosis
- About 65% of patients with GBS will fully recover with no permanent disability.
- 35% of them do not fully recover. 8% of this group will die from GBS complication and others will have permanent disabilities.
- Treatment of GBS just reduce the recovery time and doesn’t affect prognosis.[5]
- Overally, older patients will have worst prognosis in comparison to children who discover very fast.[1][2]
References
- ↑ 1.0 1.1 Hadden RD, Cornblath DR, Hughes RA, Zielasek J, Hartung HP, Toyka KV, Swan AV (November 1998). "Electrophysiological classification of Guillain-Barré syndrome: clinical associations and outcome. Plasma Exchange/Sandoglobulin Guillain-Barré Syndrome Trial Group". Ann. Neurol. 44 (5): 780–8. doi:10.1002/ana.410440512. PMID 9818934.
- ↑ 2.0 2.1 Bradshaw DY, Jones HR (April 1992). "Guillain-Barré syndrome in children: clinical course, electrodiagnosis, and prognosis". Muscle Nerve. 15 (4): 500–6. doi:10.1002/mus.880150415. PMID 1565119.
- ↑ Dornonville de la Cour C, Jakobsen J (January 2005). "Residual neuropathy in long-term population-based follow-up of Guillain-Barré syndrome". Neurology. 64 (2): 246–53. doi:10.1212/01.WNL.0000149521.65474.83. PMID 15668421.
- ↑ Meythaler JM (August 1997). "Rehabilitation of Guillain-Barré syndrome". Arch Phys Med Rehabil. 78 (8): 872–9. PMID 9344309.
- ↑ Rees JH, Thompson RD, Smeeton NC, Hughes RA (January 1998). "Epidemiological study of Guillain-Barré syndrome in south east England". J. Neurol. Neurosurg. Psychiatry. 64 (1): 74–7. PMC 2169900. PMID 9436731.