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Overview

The hallmark of Hepatic Encephalopathy is accumulation of ammonia and toxic substances in the blood that are normally detoxified in the liver. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].

History and Symptoms

Hepatic encephalopathy or portosystemic encephalopathy is a syndrome of largely reversible impairment of brain function occurring in patients with acute or chronic liver failure or when the liver is bypassed by portosystemic shunts.[1]Hepatic encephalopathy (HE) is a common problem in liver cirrhosis and is associated with typical changes of cerebral metabolite pattern observed by proton magnetic resonance spectroscopy (MRS).[2]

A positive history of Alcohol use and Viral Hepatitis is suggestive of HE. The most common symptoms of Hepatic encephalopathy include cognitive impairment, personality changes and change in consciousness. [3]

History

Patients with Hepatic Encephalopathy may have a positive history of:

  • Viral Hepatitis
  • Chronic alcohol use
  • History of drug and toxin use


  • [History finding 2]
  • [History finding 3]

Common Symptoms

Common symptoms of hepatic encephalopathy include:

  • Memory impairment
  • Personality changes
  • Coma
  • Jaundice


Hepatic encephalopathy (HE) is a common problem in liver cirrhosis and is associated with typical changes of cerebral metabolite pattern observed by proton magnetic resonance spectroscopy (MRS).[2]















































































































































































































































































































Hepatic encephalopathy (HE) is a common problem in liver cirrhosis and is associated with typical changes of cerebral metabolite pattern observed by proton magnetic resonance spectroscopy (MRS).

Less Common Symptoms

Less common symptoms of [disease name] include

  • [Symptom 2]
  • [Symptom 3]

References

  1. Schulz C, Schütte K, Vilchez-Vargas R, Vasapolli R, Malfertheiner P (November 2018). "Long-Term Effect of Rifaximin with and without Lactulose on the Active Bacterial Assemblages in the Proximal Small Bowel and Faeces in Patients with Minimal Hepatic Encephalopathy". Dig Dis: 1–9. doi:10.1159/000494216. PMID 30428474.
  2. 2.0 2.1 . PMID 30427626. Missing or empty |title= (help)
  3. Shawcross DL, Dunk AA, Jalan R, Kircheis G, de Knegt RJ, Laleman W, Ramage JK, Wedemeyer H, Morgan IE (February 2016). "How to diagnose and manage hepatic encephalopathy: a consensus statement on roles and responsibilities beyond the liver specialist". Eur J Gastroenterol Hepatol. 28 (2): 146–52. doi:10.1097/MEG.0000000000000529. PMC 4885589. PMID 26600154.

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