Wilms' tumor laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Laboratory Findings

• The following lab studies are conducted in patients suspected with wilms tumor:
  • Complete blood count (CBC)
  • Coagulation studies
    • Von Willebrand assay
      • Done in children with history of hypervascular disease or bleeding.
      • Acquired Von Willebrand's disease can be present in patients suffering from wilms tumor.
      • This is done as a precaution to risk of bleeding that can occur in case of interventions done for wilms tumor.
  • Urinalysis
  • Liver function test
    • Abnormal in case of liver metastasis of wilms tumor.
  • Serum creatinine
    • Done before and after surgical intervention.
  • Serum calcium
    • May be elevated in children suffering from rhabdoid tumor of kidney.
    • May be elevated in children suffering from congenital mesoblastic nephroma.
  • Cytogenetics studies