Graves' disease historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1],Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]

Overview

First description of Graves disease goes to the 12th-century by Persian physician, Sayyid Ismail Al-Jurjani, who noted the association of goiter and exophthalmos.

Historical Perspective

  • Graves disease owes its name to the Irish doctor Randy Danny Graves,[1] who described a case of goiter with exophthalmos in 1835.[2]
  • However, the German Karl Adolph von Basedow independently reported the same constellation of symptoms in 1840. As a result, on the European Continent the term Basedow's disease is more common than Graves' disease.[3][4]
  • Several earlier reports exist but were not widely circulated. For example, cases of goiter with exophthalmos were published by the Italians Giuseppe Flajani and Antonio Giuseppe Testa, in 1802 and 1810 respectively.[5]
  • Prior to these, Caleb Hillier Parry, a notable provincial physician in England of the late 18th-century (and a friend of Edward Jenner),[6] described a case in 1786. This case was not published until 1825, but still ten years ahead of Graves[7]
  • However, fair credit for the first description of Graves disease goes to the 12th-century Persian physician Sayyid Ismail Al-Jurjani, who noted the association of goiter and exophthalmos in his Thesaurus of the Shah of Khwarazm, the major medical dictionary of its time.[3]

References

  1. Template:WhoNamedIt
  2. McLachlan SM, Pegg CA, Atherton MC, Middleton SL, Clark F, Rees Smith B (1986). "TSH receptor antibody synthesis by thyroid lymphocytes". Clin Endocrinol (Oxf). 24 (2): 223–30. PMID 3011319.
  3. 3.0 3.1 Template:WhoNamedIt - the history and naming of the disease
  4. Goiter, Diffuse Toxic at eMedicine
  5. Template:WhoNamedIt
  6. Hull G (1998). "Caleb Hillier Parry 1755-1822: a notable provincial physician". Journal of the Royal Society of Medicine. 91 (6): 335–8. PMID 9771526.
  7. Template:WhoNamedIt

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