Secondary adrenal insufficiency primary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

There are no established measures for the primary prevention of [disease name].

OR

There are no available vaccines against [disease name].

OR

Effective measures for the primary prevention of [disease name] include [measure1], [measure2], and [measure3].

OR

[Vaccine name] vaccine is recommended for [patient population] to prevent [disease name]. Other primary prevention strategies include [strategy 1], [strategy 2], and [strategy 3].

Primary Prevention

There are no established measures for the primary prevention of secondary adrenal insufficiency. However, following measures can be effective:

  • Prevention of hypopituitarism by good obstetric care or minimizing radiation exposure.
  • Avoid the long-term use of opioids.[1]
  • Tapering of steroids as they interfere with the hypothalamic-pituitary axis which can cause secondary adrenal insufficiency.[2]

References

  1. Abs R, Verhelst J, Maeyaert J, Van Buyten JP, Opsomer F, Adriaensen H, Verlooy J, Van Havenbergh T, Smet M, Van Acker K (2000). "Endocrine consequences of long-term intrathecal administration of opioids". J. Clin. Endocrinol. Metab. 85 (6): 2215–22. doi:10.1210/jcem.85.6.6615. PMID 10852454.
  2. Joseph RM, Hunter AL, Ray DW, Dixon WG (2016). "Systemic glucocorticoid therapy and adrenal insufficiency in adults: A systematic review". Semin Arthritis Rheum. 46 (1): 133–41. doi:10.1016/j.semarthrit.2016.03.001. PMC 4987145. PMID 27105755.


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