Diabetes insipidus epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

The prevalence of diabetes insipidus is estimated to be 3:100,000 individuals worldwide. The prevalence and incidence of both central and nephrogenic DI does not vary by gender. Similarly, no significant racial predilection in prevalence among ethnic groups have been found.

With both central and nephrogenic diabetes inispidus, inherited causes account for approximately 1-2% of all cases. An incidence of about 1 in 20 million births for nephrogenic diabetes insipidus caused by AQP2 mutations has been documented.[1]

Epidemiology and Demographics

Prevalence

The prevalence of diabetes insipidus is estimated to be 3:100,000 individuals worldwide.

Incidence

The incidence of diabetes insipidus is 1 in 20 million births for nephrogenic diabetes insipidus caused by AQP2 mutations.[1]

Case Fatality Rate

The case-fatality rate of diabetes insipidus is unknown.

Age

Diabetes insipidus has been identified in all age groups from infancy to adulthood.

Gender

The prevalence and incidence of both central and nephrogenic diabetes insipidus does not vary by gender.

Race

There is no racial predilection for diabetes insipidus.

Developed countries

Incidence, prevalence, and geographical distribution of both central diabetes insipidus and nephrogenic diabetes insipidus does not vary.

Developing countries

Incidence, prevalence, and geographical distribution of both central diabetes insipidus and nephrogenic diabetes insipidus does not vary.

References

  1. 1.0 1.1 Verkman AS (2012). "Aquaporins in clinical medicine". Annu. Rev. Med. 63: 303–16. doi:10.1146/annurev-med-043010-193843. PMC 3319404. PMID 22248325.


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