Allergic colitis other imaging findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qasim Salau, M.B.B.S., FMCPaed [2]

Overview

Other imaging findings include endoscopy. Endoscopy is not recommended in the routine diagnosis of allergic colitis. Endoscopy is usually required for atypical presentation in addition to detailed clinical assessment. The lesions in allergic colitis are most often observed in the the rectosigmoid area. Gross endoscopic findings associated with allergic colitis include; focal or diffuse erythema, edematous and friable mucosa, with nodular hyperplasia and/ or ulcerations. Characteristic circumscribed central pit-like erosions may also be observed.[1][2][3]

Other Imaging Findings

Endoscopy

In allergic colitis, endoscopy is not recommended for routine diagnosis. The National Institute of Allergy and Infectious Diseases (NIAID) expert panel recommends that allergic colitis may be diagnosed based on a detailed medical history and physical examination to rule out any other possible cause for the symptoms, absence of symptoms while avoiding the causative food, and recurrence of symptoms following an oral food challenge. However, endoscopy is usually required for atypical presentation, in addition to detailed clinical findings. The most common site involved in allergic colitis is the the rectosigmoid area. Gross endoscopic findings associated with allergic colitis include:[1][2][3]

  • Focal or diffuse erythema, edematous and friable mucosa, with multiple lymphonodular hyperplasia (goose pimply appearance) and/or superficial ulcerations
  • Lymphonodular hyperplasia with characteristic circumscribed and/or central pit-like erosions may be observed especially after deflating the endoscope. These erosions may be specific findings for FPIAC[2][4]

References

  1. 1.0 1.1 Boyce JA, Assa'ad A, Burks AW, Jones SM, Sampson HA, Wood RA; et al. (2010). "Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report". J Allergy Clin Immunol. 126 (6): 1105–18. doi:10.1016/j.jaci.2010.10.008. PMC 4241958. PMID 21134568.
  2. 2.0 2.1 2.2 Hwang JB, Park MH, Kang YN, Kim SP, Suh SI, Kam S (2007). "Advanced criteria for clinicopathological diagnosis of food protein-induced proctocolitis". J Korean Med Sci. 22 (2): 213–7. doi:10.3346/jkms.2007.22.2.213. PMC 2693584. PMID 17449926.
  3. 3.0 3.1 Odze RD, Wershil BK, Leichtner AM, Antonioli DA (1995). "Allergic colitis in infants". J Pediatr. 126 (2): 163–70. PMID 7844660.
  4. Molnár K, Pintér P, Győrffy H, Cseh A, Müller KE, Arató A; et al. (2013). "Characteristics of allergic colitis in breast-fed infants in the absence of cow's milk allergy". World J Gastroenterol. 19 (24): 3824–30. doi:10.3748/wjg.v19.i24.3824. PMC 3699042. PMID 23840121.