Cementoblastoma
WikiDoc Resources for Cementoblastoma |
Articles |
---|
Most recent articles on Cementoblastoma Most cited articles on Cementoblastoma |
Media |
Powerpoint slides on Cementoblastoma |
Evidence Based Medicine |
Clinical Trials |
Ongoing Trials on Cementoblastoma at Clinical Trials.gov Trial results on Cementoblastoma Clinical Trials on Cementoblastoma at Google
|
Guidelines / Policies / Govt |
US National Guidelines Clearinghouse on Cementoblastoma NICE Guidance on Cementoblastoma
|
Books |
News |
Commentary |
Definitions |
Patient Resources / Community |
Patient resources on Cementoblastoma Discussion groups on Cementoblastoma Patient Handouts on Cementoblastoma Directions to Hospitals Treating Cementoblastoma Risk calculators and risk factors for Cementoblastoma
|
Healthcare Provider Resources |
Causes & Risk Factors for Cementoblastoma |
Continuing Medical Education (CME) |
International |
|
Business |
Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Synonyms and keywords: Synonym 1; Synonym 2; Synonym 3
Overview
Cementoblastoma (also known as benign cementoblastoma) is a relatively rare benign neoplasm of the cementum of the teeth. Cementoblastoma is derived from ectomesenchyme of odontogenic origin.[1]
Historical Perspective
- Cementoblastoma was first discovered by Norberg in 1930.
Classification
- According to the World Health Organization, cementoblastoma is classified as a true cemental neoplasm.
Pathophysiology
- The pathogenesis of cementoblastoma is characterized by originating from the root and slowly enlarging (it therefore obliterates the periodontal ligament space).
- Cementoblastoma is commonly located in the mandibular molar area.
- There are no genetic mutations associated with the development of cementoblastoma.
- On gross pathology, characteristic findings of cementoblastoma, include:
- Dense homogenous, irregular, and spherical mass.
- Tooth root
- On microscopic histopathological analysis, characteristic findings of cementoblastoma, include:
- Large globules fused to form a mass
- Composed of proliferative fibrovascular stroma
- Trabeculae lined by plump osteoblasts
Causes
- Common causes of cementoblastoma, include:
Differentiating Cementoblastoma from Other Diseases
- Cementoblastoma must be differentiated from other diseases that cause tooth pain, or swelling, such as:
- Sclerosing osteomyelitis
- Osteoblastoma
- Periapical cemental dysplasia
- Osteitis
- Hypercementosis
Epidemiology and Demographics
- Cementoblastoma is uncommon.
- Cementoblastoma accounts less than 0.69%–8% of all odontogenic tumors.
Age
- Cementoblastoma is more commonly observed among patients aged 20 to 25 years old.
- Cementoblastoma is more commonly observed among young adults.
Gender
- Cementoblastoma affects men and women equally.
Race
- There is no racial predilection for cementoblastoma.
Risk Factors
- Common risk factors in the development of cementoblastoma, include:
Natural History, Complications and Prognosis
- The majority of patients with cementoblastoma are initially asymptomatic.
- Early clinical features include tooth pain, swelling, and
- If left untreated, patients with cementoblastoma may progress to develop
- Common complications of cementoblastoma, include:
- Prognosis is generally good, and the recurrence rate of patients with cementoblastoma is approximately
Diagnosis
Symptoms
- Cementoblastoma is usually asymptomatic.
- Symptoms of cementoblastoma may include the following:
- Tooth pain
- Dentin hypersensitivity
Physical Examination
- Patients with cementoblastoma usually are well-appearing.
- Oral examination may be remarkable for:
- Swelling
- Gingival recession
- Gingivitis
Laboratory Findings
- There are no specific laboratory findings associated with cementoblastoma.
Imaging Findings
- Conventional radiograph is the imaging modality of choice for cementoblastoma.
- On conventional radiograph, characteristic findings of cementoblastoma, include:
- Well defined, markedly radiopaque mass,
- Radiolucent peripheral "line", which overlies and obliterates the tooth root.
- There is usually apparent external resorption of the root where the tumor and the root join.
- Severe hypercementosis may be present
Gallery
Treatment
Medical Therapy
- There is no treatment for cementoblastoma; the mainstay of therapy is surgery.
Surgery
- Surgery is the mainstay of therapy for cementoblastoma.
- Surgical tooth extraction in conjunction with post-surgery biopsy is the most common approach to the treatment of cementoblastoma.
Prevention
- There are no primary preventive measures available for cementoblastoma.
References
- ↑ Leena S Sankari and K Ramakrishnan, Benign cementoblastoma, Journal of Oral and Maxillofacial Pathology, 2011 Sep-Dec; 15(3): 358–360 at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227271/