Borrelia mayonii
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Historical Perspective
- February 2016 - The first description of Lyme disease caused by B. mayonii among 6 patients from Minnesota, Wisconsin, and North Dakota. The discovery was made when 6 samples (5 blood and 1 synovial fluid) out of approximately 9,000 samples suspected to have Lyme disease between 2012 and 2014 were found to contain bacteria that were genetically distinct from B. burgdorferi.
- The term mayonii refers to the Mayo Clinic medical center in Minnesota, where genetic testing for the organism was first conducted.
Associated Disease
- B. mayonii is thought to cause Lyme disease.
Differentiating B. mayonii from B. burgdorferi
The following table demonstrates key clinical and epidemiological features that distinguish B. mayonii from B. burgdorferi
B. burgdorferi | B. mayonii | |
Transmission | Tick bite | Tick bite |
Distribution in the USA | Northeast, Mid-Atlantic, and Midwest regions | Midwest region |
Bacteria Concentration in Blood (Spirochetemia) | Lower | Higher |
Early Symptoms | Fever, headache, rash, neck pain | Fever, headache, rash, neck pain |
Late Symptoms | Arthritis | Arthritis |
Nausea / Vomiting? | No | Yes |
Rash Characteristics | Bull's-eye target lesion | Diffuse rash |
Diagnosis | Serology or PCR | Serology or PCR |
Adapted from Pritt BS et al. Identification of a novel pathogenic Borrelia species causing Lyme borreliosis with unusually high spirochaetaemia: a descriptive study. Lancet Infectious Diseases. DOI: http://dx.doi.org/10.1016/S1473-3099(15)00464-8 | Centers for Disease Control and Prevention (CDC). New Lyme-disease-causing bacteria species discovered. URL: http://www.cdc.gov/media/releases/2016/p0208-lyme-disease.html. Retrieved February 9th 2016.[1]
- ↑ New Lyme-disease-causing bacteria species discovered - Centers for Disease Control and Prevention (CDC) http://www.cdc.gov/media/releases/2016/p0208-lyme-disease.html Accessed on Feb 9 2016