Mycosis fungoides medical therapy

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Cutaneous T cell lymphoma Microchapters

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Patient Information

Overview

Classification

Mycosis fungoides
Sezary syndrome

Pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Medical therapy

Medical therapy for cutaneous T cell lymphoma
Stage PUVA Topical chemotherapy Systemic chemotherapy Radiotherapy Biological therapy Retinoid therapy Photopheresis
Stage I
  • May be given
  • By itself
  • Or with interferon alfa
  • May be offered
  • May be offered
  • To 1 or 2 skin lesions (local radiation therapy)
  • Total skin electron beam therapy (TSEB)
  • May be given
  • By itself
  • Or with topical chemotherapy
  • May be offered
---------
Stage II
  • May be given
  • By itself
  • Or with interferon alfa
  • May be offered
  • May be offered
  • To 1 or 2 skin lesions (local radiation therapy)
  • Total skin electron beam therapy
  • May be given
  • By itself
  • Or with topical chemotherapy
  • May be offered
---------
Stage III
  • May be given
  • By itself
  • Or with interferon alfa
  • Or systemic chemotherapy
  • May be offered
  • May be combined with other skin-focussed therapies
  • Total skin electron beam therapy
  • As palliative therapy to reduce the size of tumours or relieve symptoms
  • May be given
  • By itself
  • Or with topical chemotherapy
  • May be offered
  • May be offered
Stage IV
  • May be given
  • By itself
  • Or with interferon alfa
  • Or systemic chemotherapy
  • May be offered
  • May be offered
  • Total skin electron beam therapy (TSEB)
  • As palliative therapy to reduce the size of tumours or relieve symptoms
  • May be given
  • By itself
  • Or with topical chemotherapy
  • May be offered
  • May be given
  • By itself
  • Or with total skin electron beam therapy
Recurrent cutaneous T cell lymphoma
  • May be offered
  • May be offered
  • May be offered
  • Total skin electron beam therapy
  • Radiation therapy to bulky tumours or lymph nodes
  • May be offered
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References


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