Neurofibroma surgery
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]
Overview
Surgery is the mainstay of treatment for neurofibroma.
Surgery
Localised neurofibroma/Diffuse neurofibroma[1]
- Localised and diffuse lesions usually be treated surgically.
- Neurofibromas that infiltrate between nerve fascicles are unable to be separated from the parent nerve, therefore, deep-seated lesions are often managed conservatively.
- Local recurrence after excision is uncommon and malignant transformation is rare.
Plexiform neurofibroma[1]
- The primary treatment option for plexiform neurofibroma is surgery.[2]
- Removal of plexiform neurofibromas is difficult because they can be large and cross tissue boundaries.
- Plexiform neurofibromas are particularly difficult to resect, often leading to incomplete resection.
- Recurrence after resection is frequent.
References
- ↑ 1.0 1.1 Neurofibroma. Dr Bruno Di Muzio and Dr Maxime St-Amant et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/neurofibroma
- ↑ Packer RJ, Gutmann DH, Rubenstein A, et al. (May 2002). "Plexiform neurofibromas in NF1: toward biologic-based therapy". Neurology. 58 (10): 1461–70. doi:10.1212/wnl.58.10.1461. PMID 12041525.