Gestational trophoblastic neoplasia history and symptoms

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Template:Choriocarcinoma Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Overview

History and Symptoms

Signs and symptoms of gestational trophoblastic disease

  • vaginal bleeding
  • swelling of the abdomen
  • With a hydatidiform mole, the abdomen and uterus may grow at a much faster rate than with a normal pregnancy.
  • ovarian cysts (luteoma)
  • nausea and vomiting
  • Some women have a condition called hyperemesis gravidarum, which causes nausea and vomiting that is often much worse than what may occur during a normal pregnancy.
  • passing of tissue resembling a “bunch of grapes” from the vagina
  • lack of fetal movement during pregnancy


Rare signs and symptoms of GTD are:

  • anemia (if bleeding is severe or lasts for a long time)
  • pre-eclampsia, a condition characterized by:
  • high blood pressure
  • abnormal amounts of protein in the urine
  • headache
  • swelling of the hands and feet
  • overactive thyroid gland (hyperthyroidism) that causes:
  • rapid heartbeat
  • warm skin
  • sweating
  • shaking
  • feeling “too hot”
  • abdominal or pelvic pain
  • vaginal discharge
  • fever

Late signs and symptoms

  • coughing up blood
  • dry cough
  • chest pain
  • trouble breathing
  • headache
  • dizziness
  • yellowing of the skin or eyes (jaundicejaundiceA condition in which the skin and whites of the eyes become yellow and urine is dark yellow.)
  • gradual loss of the ability to move a body part (paralysis)
  • seizure
  • trouble speaking
  • vision problems
  • lump in the vagina


References

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