Multiple myeloma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

In 2012, the incidence of multiple myeloma was approximately 6.3 per 100,000 cases with a mortality rate of 3.3 per 100,000 cases in the United States.[1] The prevalence of multiple myeloma was estimated to be 89,658 cases in 2012 in the United States.[2][3] Multiple myeloma is the second most common blood cancer after non-Hodgkin's lymphoma & 14th most common cancer overall in United States.[4][5][6] Male are more commonly affected with multiple myeloma than female. The male to female ratio is approximately 2 to 1.[7][8] Multiple myeloma usually affects individuals of the African American and Native Pacific Islanders race. Asian individuals are less likely to develop multiple myeloma.[9] The incidence of multiple myeloma increases with age; the median age at diagnosis is between 65 to 70 years years.[10]

Epidemiology and Demographics

Incidence

  • In 2012, the incidence of multiple myeloma waws approximately 6.3 per 100,000 individuals with a case-fatality rate of 3.3 per 100,000 in the United States.[11]
  • In 2014, multiple myeloma constituted approximately 1.4 percent of the estimated new cancer cases.[12]
  • In 2015, the estimated incidence of multiple myeloma is 1.6% of all new cancer cases and 1.9% of all cancer mortality cases.[13]
  • Multiple myeloma is the 14th leading cause of cancer death in the United States.[14]
  • Since 1975, the overall multiple myeloma incidence has increased nearly 1 percent annually.[15]

Prevalance

  • Myeloma is the 14th leading cause of cancer death in the United States.[16]
  • Multiple myeloma is the second most prevalent blood cancer (10%) after non-Hodgkin's lymphoma.[4][17]
  • There are approximately 76,000 people in the United States living with multiple myeloma. [18]
  • Multiple myeloma represents approximately 1% of all cancers and 2% of all cancer deaths.[19]
  • In 2012, there were an estimated 89,658 people living with multiple myeloma in the United States.[20]

Age

  • The incidence of multiple myeloma increases with age; the median age at diagnosis is is 65 to 70 years. Though recent statistics indicate an increase in incidence of earlier age of onset in multiple myeloma.[21]
  • Multiple myeloma is a common malignancy of older patients above 40 years old (70% of cases are diagnosed between 50 and 70 years of age.[22])

Gender

  • Male are more commonly affected with multiple myeloma than female. The male to female ratio is approximately 2 to 1.[23]

Race

  • Multiple myeloma usually affects individuals of the African American and Native Pacific Islanders race. Asian and Native Indian individuals are less likely to develop multiple myeloma.[24]
  • Among African Americans, multiple myeloma is one of the top 10 leading causes of cancer death. [25]

Gallery

Five year survival percentage

References

  1. Plasma cell neoplasm.National cancer institute (2015)http://www.cancer.gov/types/myeloma/hp/myeloma-treatment-pdq#cit/section_1.1
  2. Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  3. Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology
  4. 4.0 4.1 Collins, CD. (2005). "Problems monitoring response in multiple myeloma". Cancer Imaging. 5 Spec No A: S119–26. doi:10.1102/1470-7330.2005.0033. PMID 16361127.
  5. Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  6. Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015
  7. Multiplemyeloma.Wikipedia(2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015
  8. Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015
  9. Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015
  10. Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015
  11. Plasma cell neoplasm.National cancer institute (2015)http://www.cancer.gov/types/myeloma/hp/myeloma-treatment-pdq#cit/section_1.1
  12. A snapshot of myeloma. National cancer institute(2014)http://www.cancer.gov/research/progress/snapshots/myeloma Accessed on September, 20th 2015
  13. Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  14. Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  15. A snapshot of myeloma. National cancer institute(2014)http://www.cancer.gov/research/progress/snapshots/myeloma
  16. Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  17. Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  18. Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  19. Multiple myeloma. Wikipedia (2015) https://en.wikipedia.org/wiki/Multiple_myeloma. Accessed on September, 20th 2015
  20. Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
  21. Press Releases. Compugen (2015)http://www.cgen.com/media-center/press-releases/-314 Accessed on September, 20th 2015
  22. Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015
  23. Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015
  24. Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015
  25. Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015

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