Multiple myeloma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Multiple myeloma is the second most common blood cancer after non-Hodgkin's lymphoma & 15th most common cancer overall in United States.[1][2] Multiple myeloma is a disease of the elderly and is slightly more prevalent in men than women. It is estimated that 77,617 people currently live with multiple myeloma in the United States.[3]

Epidemiology and Demographics

Incidence

  • Since 1975, overall multiple myeloma incidence has increased nearly 1 percent annually.[4]
  • In 2012, the incidence of multiple myeloma is approximately 6.3 per 100,000 individuals with a case-fatality rate of 3.3 per 100,000.[5]
  • Results of a recent study report the incidence of multiple myeloma to be 12.3 cases per 100,000 among African Americans and 5.6 cases per 100,000 among Caucasian Americans.
  • The American Cancer Society estimates that approximately 14,600 new cases of multiple myeloma are diagnosed each year in the United States.[6]

Prevalance

  • Myeloma is the fourteenth leading cause of cancer death in the United States.[7]
  • There are approximately 76,000 people in the United States living with multiple myeloma. [8]
  • It represents approximately 1% of all cancers and 2% of all cancer deaths.
  • In 2012, there were an estimated 89,658 people living with multiple myeloma in the United States.[9]

Age

  • Multiple myeloma is the second most prevalent blood cancer (10%) after non-Hodgkin's lymphoma. Although the peak age of onset of multiple myeloma is 65 to 70 years of age, recent statistics report increasing incidence as well as earlier age of onset of multiple myeloma.

Gender

  • Multiple myeloma affects slightly more men than women.

Race

  • African Americans and non Hispanics have the highest reported incidence of multiple myeloma in the United States while Asians and American Indians have the lowest
  • Among African Americans, multiple myeloma is one of the top 10 leading causes of cancer death. [10]

References

  1. Collins, CD. (2005). "Problems monitoring response in multiple myeloma". Cancer Imaging. 5 Spec No A: S119–26. doi:10.1102/1470-7330.2005.0033. PMID 16361127.
  2. "Myeloma - SEER Stat Fact Sheets". Retrieved 17 February 2014.
  3. "Myeloma - SEER Stat Fact Sheets". Retrieved 17 February 2014.
  4. A snapshot of myeloma. National cancer institute(2014)http://www.cancer.gov/research/progress/snapshots/myeloma
  5. Plasma cell neoplasm.National cancer institute (2015)http://www.cancer.gov/types/myeloma/hp/myeloma-treatment-pdq#cit/section_1.1
  6. "Myeloma - SEER Stat Fact Sheets". Retrieved 17 February 2014.
  7. Seer stat fact sheet:Myeloma. http://seer.cancer.gov/statfacts/html/mulmy.html
  8. "Myeloma - SEER Stat Fact Sheets". Retrieved 17 February 2014.
  9. Seer stat fact sheet:Myeloma. http://seer.cancer.gov/statfacts/html/mulmy.html
  10. "Myeloma - SEER Stat Fact Sheets". Retrieved 17 February 2014.

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