Endometrial cancer natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Overview

Natural History

Complications

  • A perforation (hole) of the uterus may occur during a D&C or an endometrial biopsy.

Prognosis

Because endometrial cancer is usually diagnosed in the early stages (70 % to 75 % of cases are in stage 1 at diagnosis; 10 % to 15 % of cases are in stage 2; 10 % to 15 % of cases are in stage 3 or 4), there is a better probable outcome associated with it than with other types of gynecological cancers such as cervical or ovarian cancer. While endometrial cancers are 40% more common in Caucasian women, an African American woman who is diagnosed with uterine cancer is twice as likely to die, possibly due to the higher frequency of aggressive subtypes in that population.

Survival rates

The 5-year survival rate for endometrial cancer following appropriate treatment is:

  • 75% to 95% for stage 1
  • 50% for stage 2
  • 30% for stage 3
  • less than 5% for stage 4

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