Multiple myeloma history and symptoms
|
Multiple myeloma Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Multiple myeloma history and symptoms On the Web |
|
American Roentgen Ray Society Images of Multiple myeloma history and symptoms |
|
Risk calculators and risk factors for Multiple myeloma history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The signs and symptoms of multiple myeloma are most commonly associated with either elevation in calcium concentrations, renal failure, anemia and involvement of the bones such as fractures and pains.
History and Symptoms
Early multiple myeloma does not have any symptoms. In as many as 30-40% cases the diagnosis may be incidental and is often diagnosed on routine blood screening. A rise in total protein levels without a concomitant rise in albumin levels must make the physician suspicious for a possibility of multiple myeloma. As the tumor grows larger, people may notice one or more of the following symptoms:
- Bone pain
- Pathological fractures
- Numbness and/or muscle weakness
- Confusion
- Dizziness
- Edema in legs
- Back pain, numbness, dysthesias suggestive of spinal cord compression.
- Bleeding
- Recurrent infections