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Bronchiolitis

Treatment

Note[1]

Prophylaxis

Note
  • Clinicians should administer palivizumab during the first year of life to infants with hemodynamically significant heart disease or chronic lung disease of prematurity defined as preterm infants <32 weeks 0 days’ gestation who require >21% oxygen for at least the first 28 days of life.
  • Clinicians should not administer palivizumab to otherwise healthy infants with a gestational age of 29 weeks, 0 days or greater.
  • All people should disinfect hands before and after direct contact with patients, after contact with inanimate objects in the direct vicinity of the patient, and after removing gloves.
  • All people should use alcoholbased rubs for hand decontamination when caring for children with bronchiolitis. When alcoholbased rubs are not available, individuals should wash their hands with soap and water.
  • Clinicians should counsel caregivers about exposing the infant or child to environmental tobacco smoke and smoking cessation when assessing a child for bronchiolitis.


Influenza

Treatment

  • Preferred Regimen(1): Zanamivir 10 mg (two 5-mg inhalations) BID for 5 days.
  • Preferred Regimen(2): Oseltamivir 75 mg BID for 5 days.
  • Preferred Regimen(3): Peramivir one 600 mg dose, via intravenous infusion for 15-30 minutes for 1 day.

Prophylaxis

  • The chemoprophylaxis dosage of Zanamivir is 10 mg (2 inhalations) once a day.
  • The chemoprophylaxis of Oseltamivir is from 3 months and older age group.
  • Pediatric dose

Oseltamivir If younger than 1 yr old1: 3 mg/kg/dose twice daily2,3 If 1 yr or older, dose varies by child’s weight: 15 kg or less, the dose is 30 mg twice a day >15 to 23 kg, the dose is 45 mg twice a day>23 to 40 kg, the dose is 60 mg twice a day>40 kg, the dose is 75 mg twice a day.

Zanamivir 10 mg (two 5-mg inhalations) twice daily (FDA approved and recommended for use in children 7 yrs or older).

  1. Ralston SL, Lieberthal AS, Meissner HC, Alverson BK, Baley JE, Gadomski AM; et al. (2014). "Clinical practice guideline: the diagnosis, management, and prevention of bronchiolitis". Pediatrics. 134 (5): e1474–502. doi:10.1542/peds.2014-2742. PMID 25349312.