Sandbox g19

Brain abscess

• Empiric antimicrobial therapy

• Brain abscess in otherwise healthy patients

• Preferred regimen

• Cefotaxime 8–12 g/day IV q4–6h OR Ceftriaxone 4 g/day IV q12h AND Metronidazole 30 mg/kg/day IV q6h

• Alternative regimen

• Meropenem 6 g/day IV q8h

• Brain abscess with comorbidities