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Epidural abscess

  • Spinal epidural abscess[1]
  • Empiric antimicrobial therapy
Note (1): Decompressive laminectomy in conjunction with long-term antibiotic therapy tailored to culture results is required.
Note (2): For critically ill patients, a vancomycin loading dose of 20–25 mg/kg may be considered.
  • Culture-directed antimicrobial therapy
  • Penicillin-susceptible strain
  • Oxacillin-susceptible strain
  • Preferred regimen: Oxacillin 2 g IV q4h for 6 weeks

Brain abscess

  • Brain abscess, bacterial[2]
  • Empiric antimicrobial therapy
  • Preferred regimen: Vancomycin AND (Cefotaxime 2 g IV q4h OR Ceftriaxone 2 g IV q12h) AND (Metronidazole 7.5 mg/kg q6h or 15 mg/kg q12h)



  • Brain abscess, tuberculous


  • Brain abscess, fungal

References

  1. Kasper, Dennis (2015). Harrison's principles of internal medicine. New York: McGraw Hill Education. ISBN 978-0071802154.
  2. Bennett, John (2015). Mandell, Douglas, and Bennett's principles and practice of infectious diseases. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1455748013.