Targeted temperature management

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Robert G. Badgett, M.D.[1]

Targeted temperature management, also called therapeutic hypothermia or induced hypothermia, is "Abnormally low body temperature that is intentionally induced in warm-blooded animals by artificial means. In humans, mild or moderate hypothermia has been used to reduce tissue damages, particularly after cardiac or spinal cord injuries and during subsequent surgeries."[1]

Effectiveness

Clinical practice guidelines summarize management.[2]

A systematic review by the Cochrane Collaboration suggests benefit.[3] A second systematic review focusing on survivors of non-shockable rhythms suggests benefit.[4]

See also

References

  1. Anonymous (2024), Hypothermia, Induced (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. ECC Committee, Subcommittees and Task Forces of the American Heart Association (2005). "2005 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care". Circulation. 112 (24 Suppl): IV1–203. doi:10.1161/CIRCULATIONAHA.105.166550. PMID 16314375.
  3. Arrich J, Holzer M, Havel C, Müllner M, Herkner H (2012). "Hypothermia for neuroprotection in adults after cardiopulmonary resuscitation". Cochrane Database Syst Rev. 9: CD004128. doi:10.1002/14651858.CD004128.pub3. PMID 22972067.
  4. Kim YM, Yim HW, Jeong SH, Klem ML, Callaway CW (2012). "Does therapeutic hypothermia benefit adult cardiac arrest patients presenting with non-shockable initial rhythms?: A systematic review and meta-analysis of randomized and non-randomized studies". Resuscitation. 83 (2): 188–96. doi:10.1016/j.resuscitation.2011.07.031. PMID 21835145.

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