Seminoma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Testicular germ cell tumor accounts for around 1-2% of all malignancies in males up to the age of 65, but they are the most common nonhematologic malignancy in males 15-49 years old. Approximately 50% of germ cell tumours are seminomas. The mean age at diagnosis of testicular seminoma is between 15 and 35 years. This is about 5 to 10 years older than men with other germ cell tumors of the testis. Testicular seminoma usually affects individuals of the Caucasian race. African american individuals are less likely to develop testicular seminoma.

Epidemiology

Prevalence

Testicular germ cell tumor accounts for around 1-2% of all malignancies in males up to the age of 65, but they are the most common nonhematologic malignancy in males 15-49 years old. Approximately 50% of germ cell tumours are seminomas.[1]

Age

The mean age at diagnosis of testicular seminoma is between 15 and 35 years. This is about 5 to 10 years older than men with other germ cell tumors of the testis.[2]

Race

Testicular seminoma usually affects individuals of the Caucasian race. African american individuals are less likely to develop testicular seminoma.[1]

Epidemiology and Demographics

Incidence

  • The prevalence of seminoma is approximately per 100,000 individuals worldwide.
  • In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.

Prevalence

  • The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
  • In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
  • The prevalence of [disease/malignancy] is estimated to be [number] cases annually.

Case-fatality rate/Mortality rate

  • In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
  • The case-fatality rate/mortality rate of [disease name] is approximately [number range].

Age

  • Seminoma commonly affects individuals young adults 15 and 35 years of age.[3]
  • Seminoma is usually first diagnosed among 34 years (median, 39.5 years).[4]

Race

  • Seminoma usually affects individuals of the white race. Black individuals are less likely to develop seminoma (ratio of 5 : 1).[5]

Gender

  • Seminoma affects exclusively in men.

Region

  • The majority of seminoma cases are reported in Europe, Scandinavia and North America.[6]

References

  1. 1.0 1.1 Epidemiology of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016
  2. Presentation of seminoma. Wikipedia 2016. https://en.wikipedia.org/wiki/Seminoma. Accessed on February 25, 2016
  3. Che, Mingxin; Tamboli, Pheroze; Ro, Jae Y.; Park, Dong Soo; Ro, Jung Sil; Amato, Robert J.; Ayala, Alberto G. (2002). "Bilateral testicular germ cell tumors". Cancer. 95 (6): 1228–1233. doi:10.1002/cncr.10804. ISSN 0008-543X.
  4. Di Gregorio M, Nollevaux MC, Lorge F, D'Hondt L (May 2016). "Metachronous testicular seminoma after radiotherapy and chemotherapy: a case report". World J Surg Oncol. 14: 147. doi:10.1186/s12957-016-0902-9. PMC 4867539. PMID 27184033.
  5. McGlynn KA, Cook MB (November 2009). "Etiologic factors in testicular germ-cell tumors". Future Oncol. 5 (9): 1389–402. doi:10.2217/fon.09.116. PMC 3000220. PMID 19903067.
  6. Shanmugalingam T, Soultati A, Chowdhury S, Rudman S, Van Hemelrijck M (October 2013). "Global incidence and outcome of testicular cancer". Clin Epidemiol. 5: 417–27. doi:10.2147/CLEP.S34430. PMC 3804606. PMID 24204171.

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