ZMYND11

Zinc finger, MYND domain containing 11
Identifiers
Symbols	ZMYND11 ; BRAM1; BS69; MGC111056; RP11-486H9.1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 4828
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE ZMYND11 202136 at tn.png
File:PBB GE ZMYND11 202137 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Zinc finger, MYND domain containing 11, also known as ZMYND11, is a human gene.

The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified.

Further reading

• Hateboer G, Gennissen A, Ramos YF; et al. (1995). "BS69, a novel adenovirus E1A-associated protein that inhibits E1A transactivation". EMBO J. 14 (13): 3159–69. PMID 7621829.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. PMID 8889548.CS1 maint: Multiple names: authors list (link)
• Kurozumi K, Nishita M, Yamaguchi K; et al. (1998). "BRAM1, a BMP receptor-associated molecule involved in BMP signalling". Genes Cells. 3 (4): 257–64. PMID 9663660.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Masselink H, Bernards R (2000). "The adenovirus E1A binding protein BS69 is a corepressor of transcription through recruitment of N-CoR". Oncogene. 19 (12): 1538–46. doi:10.1038/sj.onc.1203421. PMID 10734313.
• Lo KW, Naisbitt S, Fan JS; et al. (2001). "The 8-kDa dynein light chain binds to its targets via a conserved (K/R)XTQT motif". J. Biol. Chem. 276 (17): 14059–66. doi:10.1074/jbc.M010320200. PMID 11148209.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ansieau S, Leutz A (2002). "The conserved Mynd domain of BS69 binds cellular and oncoviral proteins through a common PXLXP motif". J. Biol. Chem. 277 (7): 4906–10. doi:10.1074/jbc.M110078200. PMID 11733528.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wei G, Schaffner AE, Baker KM; et al. (2003). "Ets-2 interacts with co-repressor BS69 to repress target gene expression". Anticancer Res. 23 (3A): 2173–8. PMID 12894593.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hughes-Davies L, Huntsman D, Ruas M; et al. (2004). "EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer". Cell. 115 (5): 523–35. PMID 14651845.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Deloukas P, Earthrowl ME, Grafham DV; et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Colland F, Jacq X, Trouplin V; et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMID 15231748.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Isobe T, Uchida C, Hattori T; et al. (2006). "Ubiquitin-dependent degradation of adenovirus E1A protein is inhibited by BS69". Biochem. Biophys. Res. Commun. 339 (1): 367–74. doi:10.1016/j.bbrc.2005.11.028. PMID 16300738.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wan J, Zhang W, Wu L; et al. (2006). "BS69, a specific adaptor in the latent membrane protein 1-mediated c-Jun N-terminal kinase pathway". Mol. Cell. Biol. 26 (2): 448–56. doi:10.1128/MCB.26.2.448-456.2006. PMID 16382137.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Velasco G, Grkovic S, Ansieau S (2006). "New insights into BS69 functions". J. Biol. Chem. 281 (24): 16546–50. doi:10.1074/jbc.M600573200. PMID 16565076.CS1 maint: Multiple names: authors list (link)