Pyelonephritis secondary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview=

Pyelonephritis can be prevented secondarily in some cases by giving long term prophylactic antibiotics. Correction of a structural defect that lead to the initial episode of pyelonephritis may also be helpful in eliminating chances of recurrence of Pyelonephritis.

Secondary Prevention

  • If no structural or functional abnormality is identified, some studies suggest long-term preventative (prophylactic) treatment with antibiotics, either daily or after sexual intercourse.[1]
  • In children at risk of recurrent UTIs, the evidence is inconclusive as to whether long-term prophylactic antibiotics are of use.[2]
  • Ingestion of cranberry juice has been studied as a prophylactic measure; while studies are heterogeneous, many suggest a benefit.[3]

References

  1. Schooff M, Hill K (2005). "Antibiotics for recurrent urinary tract infections". American family physician. 71 (7): 1301–2. PMID 15832532.
  2. Williams GJ, Wei L, Lee A, Craig JC (2006). "Long-term antibiotics for preventing recurrent urinary tract infection in children". Cochrane database of systematic reviews (Online). 3: CD001534. doi:10.1002/14651858.CD001534.pub2. PMID 16855971.
  3. Raz R, Chazan B, Dan M (2004). "Cranberry juice and urinary tract infection". Clin. Infect. Dis. 38 (10): 1413–9. doi:10.1086/386328. PMID 15156480.


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