Caplans syndrome differential diagnosis
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: {[ Sharmi Biswas,MBBS}]
Overview
Caplan syndrome must be differentiated from asbestosis, silicosis, and tuberculosis.
Differentiating Caplan syndrome from other Diseases
Caplan syndrome must be differentiated from asbestosis, silicosis and other respiratory diseases with lung lesions.
Disease | Findings |
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Bacterial pneumonia | Sudden onset of symptoms, such as high fever, cough, purulent sputum, chest pain, leukocytosis, chest X-ray shows consolidation. |
Bronchogenic carcinoma | may be asymptomatic, usually at older ages (> 50 years old), cough, hemoptysis, weight loss |
Brucellosis | Fever, anorexia, night sweats, malaise,back pain , headache, and depression. History of exposure to infected animal |
Hodgkin lymphoma | Fever, night sweats, pruritus, painless adenopathy, mediastinal mass |
Mycoplasmal pneumonia | Gradual onset of dry cough, headache, malaise, sore throat. Diffuse bilateral infiltrates on chest X-ray. |
Sarcoidosis | Non-caseating granulomas in lungs and other organs, bilateral hilar lymphadenopathy, mostly in African American females. |
Caplan syndrome | Initially asymptomatic but advanced stages are associated with shortness of breath, cough and wheeze in the chest. Mostly in miners with preexisting rheumatoid arthritis. |
Adapted from Mandell, Douglas, and Bennett's principles and practice of infectious diseases 2010 [1] |
Causes of
lung cavities |
Differentiating Features | Differentiating radiological findings | Diagnosis
confirmation |
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Caplan syndrome |
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References
- ↑ Mandell, Gerald (2010). Mandell, Douglas, and Bennett's principles and practice of infectious diseases. Philadelphia, PA: Churchill Livingstone/Elsevier. ISBN 0443068399.
- ↑ 2.0 2.1 Chaudhuri MR (1973). "Primary pulmonary cavitating carcinomas". Thorax. 28 (3): 354–66. PMC 470041. PMID 4353362.
- ↑ Langford CA, Hoffman GS (1999). "Rare diseases.3: Wegener's granulomatosis". Thorax. 54 (7): 629–37. PMC 1745525. PMID 10377211.
- ↑ Al-Ghanem S, Al-Jahdali H, Bamefleh H, Khan AN (2008). "Bronchiolitis obliterans organizing pneumonia: pathogenesis, clinical features, imaging and therapy review". Ann Thorac Med. 3 (2): 67–75. doi:10.4103/1817-1737.39641. PMC 2700454. PMID 19561910.
- ↑ Schreiber, J.; Koschel, D.; Kekow, J.; Waldburg, N.; Goette, A.; Merget, R. (2010). "Rheumatoid pneumoconiosis (Caplan's syndrome)". European Journal of Internal Medicine. 21 (3): 168–172. doi:10.1016/j.ejim.2010.02.004. ISSN 0953-6205.