Sandbox:Nuha
Table 1. Risk Score For Drug-Associated QTc Prolongation
| Risk Factors | Points |
|---|---|
| Age ≥68 y
|
1
|
| Female sex | 1 |
| Loop diuretic | 1 |
| Serum K+ ≤3.5 mEq/L | 2 |
| Admission QTc ≥450 ms | 2 |
| Acute MI | 2 |
| ≥2 QTc-prolonging drugs | 3 |
| sepsis | 3 |
| Heart failure | 3 |
| One QTc-prolonging drug | 3 |
| Maximum Risk Score | 21 |
| K+ indicates potassium; and MI, myocardial infarction. |
A Tisdale score of ≤ 6 predicts low risk, 7-10 medium risk, and ≥ 11 high risk of drug-associated QT prolongation (Table 2).
| Table 2. Risk Levels For Drug-Associated QT Prolongation |
|---|
| Low risk = ≤6 points |
| Moderate risk = 7-10 points |
| High-risk = ≥11 points |