Ascariasis natural history

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Fatimo Biobaku M.B.B.S [2]

Overview

Ascariasis is often asymptomatic.[1] Complications may arise when adult worms move to certain organs such as the bile duct, pancreas, or appendix..[1] A high worm burden can also result in complications such as intestinal obstruction.[2]

Natural History

The majority of people infected with Ascaris are asymptomatic although greater than 15% can experience some type of morbidity.[1]

Complications

Complications of ascariasis include the following:[3][2][4]

  • Biliary duct disease
  • Hepatic abscess
  • Intestinal obstruction associated with perforation, volvulus, and intussusception
  • Peritonitis
  • Pancreatitis
  • Acute appendicitis
  • Malabsorption and growth impairment from chronic infection with Ascaris lumbricoides
  • Interstitial nephritis and acute renal failure (rare)
  • Acute eosinophilic pneumonia resulting in respiratory distress (rare)

Prognosis

Most infection are asymptomatic but mortality can be as high as 60,000 per year.[1]

References

  1. 1.0 1.1 1.2 1.3 Durand, Marlene (2015). "Chapter 288:Intestinal Nematodes (Roundworms)". Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases Updated Edition, Eighth Edition. Elsevier. pp. 3199–3207. ISBN 978-1-4557-4801-3.
  2. 2.0 2.1 Kliegman, Robert; Stanton, Bonita; St. Geme, Joseph; Schor, Nina (2016). "Chapter 291:Ascariasis (Ascaris lumbricoides)". Nelson Textbook of Pediatrics Twentieth Edition. Elsevier. pp. 1733–1734. ISBN 978-1-4557-7566-8.
  3. Ferri, Fred (2017). "Chapter:Ascariasis". Ferri's Clinical Advisor 2017. Elsevier. pp. 117–117. ISBN 978-0-3232-8048-8.
  4. Kim, Kami; Weiss, Louis; Tanowitz, Herbert (2016). "Chapter 39:Parasitic Infections". Murray and Nadel's Textbook of Respiratory Medicine Sixth Edition. Elsevier. pp. 682–698. ISBN 978-1-4557-3383-5.


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