Allergic colitis laboratory findings
Allergic colitis Microchapters |
Diagnosis |
Treatment |
Allergic colitis laboratory findings On the Web |
American Roentgen Ray Society Images of Allergic colitis laboratory findings |
Risk calculators and risk factors for Allergic colitis laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qasim Salau, M.B.B.S., FMCPaed [2]
Overview
There are no specific laboratory findings that are pathognomonic of allergic colitis. Laboratory studies should therefore be correlated with a carefully taken history and a detailed physical examination. Presence of eosinophils in the stool is suggestive of allergic colitis in the presence of typical clinical findings.[1][2][3]
Laboratory Findings
There are no specific diagnostic laboratory findings associated with allergic colitis. Laboratory studies should therefore be correlated with a carefully taken history and a detailed physical examination.[1][2][3]
Stool microscopy
- Presence of blood, either frank or occult blood
- May show increased eosinophils which is suggestive of allergic colitis in the presence of typical clinical findings
Complete Blood Count with Differentials and Peripheral Blood Smear
- A low hemoglobin or hematocrit with microcytosis or marginal normocytosis may be seen and indicative of iron deficiency anemia from blood loss
- Peripheral blood eosinophilia may rarely be seen especially in FPIES
- Elevated white blood cells with a left shift may be seen in severe acute FPIES
Iron studies
- Low ferritin with a high TIBC is suggestive of chronic blood loss by inflammatory bowel disease.
- High ferritin may be suggestive of anemia of chronic inflammatory conditions
Complete Metabolic Panel
- May show hypoalbuminemia especially in children with chronic FPIES
- Metabolic acidosis may be seen in FPIES
References
- ↑ 1.0 1.1 Fiocchi A, Brozek J, Schünemann H, Bahna SL, von Berg A, Beyer K; et al. (2010). "World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines". Pediatr Allergy Immunol. 21 Suppl 21: 1–125. doi:10.1111/j.1399-3038.2010.01068.x. PMID 20618740.
- ↑ 2.0 2.1 Pumberger W, Pomberger G, Geissler W (2001). "Proctocolitis in breast fed infants: a contribution to differential diagnosis of haematochezia in early childhood". Postgrad Med J. 77 (906): 252–4. PMC 1741985. PMID 11264489.
- ↑ 3.0 3.1 Nowak-Węgrzyn A (2015). "Food protein-induced enterocolitis syndrome and allergic proctocolitis". Allergy Asthma Proc. 36 (3): 172–84. doi:10.2500/aap.2015.36.3811. PMC 4405595. PMID 25976434.