Acute respiratory distress syndrome risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Brian Shaller, M.D. [2]
Overview
The most potent risk factor in the development of ARDS is chronic alcoholism.[1][2] Other risk factors include advanced age, cigarette smoke exposure, and chronic liver disease.
Risk Factors
The most potent risk factor in the development of ARDS is chronic alcoholism.[1][2] Other risk factors include:[3]
- Advanced age
- Alcoholic liver disease
- History of prior lung disease (chronic obstructive pulmonary disease, interstitial lung disease, etc.)
- Unexplained hypotension (systolic blood pressure < 90 mm Hg for > 2 hours)
- Low systemic vascular resistance (< 800 dynes/s/cm5)
- Metabolic acidosis with anion gap > 20 mEq/L or base deficit > 5 mEq/L
- Chronic kidney disease
- Cigarette smoke exposure
- Hypoalbuminemia
- HIV
- Organ transplantation
References
- ↑ 1.0 1.1 Moss M, Bucher B, Moore FA, Moore EE, Parsons PE (1996). "The role of chronic alcohol abuse in the development of acute respiratory distress syndrome in adults". JAMA. 275 (1): 50–4. PMID 8531287.
- ↑ 2.0 2.1 Moss M, Burnham EL (2003). "Chronic alcohol abuse, acute respiratory distress syndrome, and multiple organ dysfunction". Crit Care Med. 31 (4 Suppl): S207–12. doi:10.1097/01.CCM.0000057845.77458.25. PMID 12682442.
- ↑ Mangialardi RJ, Martin GS, Bernard GR, Wheeler AP, Christman BW, Dupont WD; et al. (2000). "Hypoproteinemia predicts acute respiratory distress syndrome development, weight gain, and death in patients with sepsis. Ibuprofen in Sepsis Study Group". Crit Care Med. 28 (9): 3137–45. PMID 11008971.