Gestational trophoblastic neoplasia history and symptoms

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Template:Choriocarcinoma Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

History

The medical history is a record of present symptoms, risk factors and all the medical events and problems a person has had in the past. The medical history of a person’s family may also help the doctor to diagnose GTD. In taking a medical history, the doctor will ask questions about:

  • A personal history of
  • Previous pregnancies, including hydatidiform mole (molar pregnancy) and miscarriage
  • Previous GTD
  • Reproductive factors that may increase the risk of GTD
  • A family history of GTD
  • Signs and symptoms that may suggest GTD

Symptoms

Symptoms of gestational trophoblastic disease

  • Vaginal bleeding
  • Swelling of the abdomen
  • With a hydatidiform mole, the abdomen and uterus may grow at a much faster rate than with a normal pregnancy
  • Nausea and vomiting or hyperemesis gravidarum
  • Passing of tissue resembling a “bunch of grapes” from the vagina
  • Absent fetal movement during pregnancy

Rare symptoms of GTD are:

  • Headache
  • Edema of the hands and feet
  • Abdominal or pelvic pain
  • Vaginal discharge
  • Overactive thyroid gland (hyperthyroidism) that causes:

Late symptoms

References

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