Non small cell lung cancer medical therapy stage II: Difference between revisions
No edit summary |
|||
Line 28: | Line 28: | ||
{{familytree | E01 | | E02 | | | E01=Yes|E02=No}} | {{familytree | E01 | | E02 | | | E01=Yes|E02=No}} | ||
{{familytree | |!| | | |!| | | | |}} | {{familytree | |!| | | |!| | | | |}} | ||
{{familytree | F01 | | F02 | | | F01=[[Non small cell carcinoma of the lung medical therapy stage III|Click here for the stage III treatment]]|F02=Is the tumor operable?}} | {{familytree | F01 | | F02 | | | F01=[[Non small cell carcinoma of the lung medical therapy stage III|Click here for the stage III treatment]]|F02=Is the [[tumor]] operable?}} | ||
{{familytree | | | |,|-|^|-|.| | |}} | {{familytree | | | |,|-|^|-|.| | |}} | ||
{{familytree | | | G01 | | G02 | | G01=Yes|G02=No}} | {{familytree | | | G01 | | G02 | | G01=Yes|G02=No}} | ||
Line 36: | Line 36: | ||
{{familytree | | | | | I01 | | I02 | | | | | I01=Yes|I02=No|I03=Initiate neoadjuvant[[Non small cell carcinoma of the lung chemotherapy#Chemotherapy plus radiation therapy|chemotherapy + radiation therapy]]|I04=Is the [[tumor]] resectable?}} | {{familytree | | | | | I01 | | I02 | | | | | I01=Yes|I02=No|I03=Initiate neoadjuvant[[Non small cell carcinoma of the lung chemotherapy#Chemotherapy plus radiation therapy|chemotherapy + radiation therapy]]|I04=Is the [[tumor]] resectable?}} | ||
{{familytree | | | | | |!| | | |!| | |}} | {{familytree | | | | | |!| | | |!| | |}} | ||
{{familytree | | | | | J01 | | J02 | | J01=[[Non small cell carcinoma of the lung chemotherapy#Chemotherapy plus | {{familytree | | | | | J01 | | J02 | | J01=[[Non small cell carcinoma of the lung chemotherapy#Chemotherapy plus Radiation Therapy|chemotherapy + radiation therapy]]|J02=[[Non small cell carcinoma of the lung medical therapy radiation therapy|radiation therapy with stereotactic ablative radiotherapy]]<br>Adjuvant [[Non small cell carcinoma of the lung chemotherapy|Chemotherapy]] should be added for high-risk stages}} | ||
{{familytree/end}} | {{familytree/end}} | ||
<br> | <br> |
Revision as of 14:37, 26 June 2014
Non Small Cell Lung Cancer Microchapters |
Differentiating Non Small Cell Lung Cancer from other Diseases |
---|
Diagnosis |
Treatment |
Case Studies |
Non small cell lung cancer medical therapy stage II On the Web |
American Roentgen Ray Society Images of Non small cell lung cancer medical therapy stage II |
Non small cell lung cancer medical therapy stage II in the news |
Blogs on Non small cell lung cancer medical therapy stage II |
Directions to Hospitals Treating Non small cell carcinoma of the lung |
Risk calculators and risk factors for Non small cell lung cancer medical therapy stage II |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alonso Alvarado, M.D. [2]
Overview
Medical Therapy for Stage II Non-Small Cell Lung Cancer
Stage IIA
Shown below is the algorithm on the treatment of the stage IIA non-small cell lung cancer based on the 2014 NCCN Non-Small Cell Lung Cancer guidelines.[1]
| |||||||||||||||||||||||||||||
Perform a pretreatment evaluation
| |||||||||||||||||||||||||||||
Does the pathological evaluation showed positive disease in the mediastinal lymph nodes? | |||||||||||||||||||||||||||||
Yes | No | ||||||||||||||||||||||||||||
Click here for the stage III treatment | Is the tumor operable? | ||||||||||||||||||||||||||||
Yes | No | ||||||||||||||||||||||||||||
Surgical resection + lymph node dissection | Does the patient presents metastasis to ipsilateral peribronchial and/or hiliar nodes and intrapulmonar nodes (N1)? | ||||||||||||||||||||||||||||
Yes | No | ||||||||||||||||||||||||||||
chemotherapy + radiation therapy | radiation therapy with stereotactic ablative radiotherapy Adjuvant Chemotherapy should be added for high-risk stages | ||||||||||||||||||||||||||||
Stage IIB
Shown below is the algorithm on the treatment of the stage IIB non-small cell lung cancer based on the 2014 NCCN Non-Small Cell Lung Cancer guidelines.[1]
Perform a pretreatment evaluation
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
What is the location of the tumor? | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Superior suculus tumor | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
T3 (Invasion to adjacent structures), N0 | Preferred option: Surgery + pathological determination of microscopic residual tumor | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Neoadjuvant chemotherapy | Are margins from the surgical piece positive or negative for residual tumor? | Perform surgery + pathological determination of residual tumor | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Surgery + adjuvant chemotherapy | Negative (R0) | Positive: Is the residual tumor microscopic (R1) or macroscopic (R2) | Are margins from the surgical piece positive or negative for residual tumor? | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Adjuvant chemotherapy | Microscopic (R1) | Macroscopic (R2) | Negative (R0) | Positive (R1-2) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Tumor resection + adjuvant chemotherapy OR chemotherapy + radiation therapy, followed or not by chemotherapy | Tumor resection + adjuvant chemotherapy OR chemotherapy + radiation therapy | Observation | Tumor resection | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||