Venous thromboembolism prevention resident survival guide: Difference between revisions

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{{familytree  | H01 | | H02 | H01= Substitute mechanical prophylaxis by pharmacological prophylaxis| H02= Continue mechanical prophylaxis}}
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====Assessment of Risk of VTE in Hospitalized Patients====


===Critically Ill Hospitalized Patients===
===Critically Ill Hospitalized Patients===

Revision as of 14:13, 23 May 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]

Overview

VTE Prevention in Non Surgical Patients

Hospitalized Acutely Ill Medical Patients

Shown below is the indications and choices of VTE prophylaxis among acutely ill patients. If VTE prophylaxis is recommended, it should be administered for the period of immobilization or hospital stay. Do not extend the duration of the prophylaxis after the period of immobilization or hospital stay.[1]

 
 
 
 
 
What is the risk of thrombosis in the acutely ill patient?
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
High
 
Low
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Is the patient bleeding or at high risk of bleeding?
 
No VTE prophylaxis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Yes
 
No
 
 
 
 
 
 
 
 
 
 
 
 
Mechanical VTE prophylaxis
For the period of immobilization or hospital stay only
Graduated compression stocking
Intermittent pneumatic compression
 
Pharmacological VTE prophylaxis
For the period of immobilization or hospital stay only
LMWH
Low dose UFH, BID
Low dose UFH, TID
Fondaparinux
 
 
 
 
 
 
 
 
 
 
 
Did the bleeding or bleeding risk subside
AND
the patient is still at increased risk of thrombosis?
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Yes
 
No
 
 
 
 
 
 
 
 
 
 
Substitute mechanical prophylaxis by pharmacological prophylaxis
 
Continue mechanical prophylaxis

Assessment of Risk of VTE in Hospitalized Patients

Critically Ill Hospitalized Patients

Shown below is an algorithm depicting the choices for VTE prophylaxis among critically ill patients. Note that routine ultrasound screening for DVT is not recommended among critically ill patients. Do not extend the duration of the prophylaxis after the period of immobilization or hospital stay.[1]

 
 
 
Is the critically ill patient bleeding or at risk for major bleeding?
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Yes
 
No
 
 
 
 
 
 
 
 
 
 
 
 
Mechanical VTE prophylaxis
Graduated compression stocking
Intermittent pneumatic compression
 
Pharmacological VTE prophylaxis
LMWH
Low dose UFH
 
 
 
 
 
 
 
 
 
 
 
Did the bleeding or bleeding risk subside?
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Yes
 
No
 
 
 
 
 
 
 
 
 
 
Substitute mechanical prophylaxis by pharmacological prophylaxis
 
Continue mechanical prophylaxis

Cancer in Outpatient

Shown below is an algorithm depicting VTE prophylaxis among cancer patients. Note that, cancer patients with indwelling central venous catheters do not require VTE prophylaxis with neither LMWH, low dose unfractionated heparin or vitamin K antagonists.[1]

 
 
❑ Does the patient have a solid tumor
AND
❑ Additional risk factors for VTE?
❑ Previous VTE
❑ Hormonal therapy
❑ Immobilization
❑ Angiogenesis inhibitors
❑ Thalidomide
❑ Lenalidomide
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Yes
 
No
 
 
 
 
 
 
 
 
 
 
 
Pharmacological VTE prophylaxis
LMWH
Low dose UFH
 
No VTE prophylaxis
 

Chronically Immobilized Patients

No VTE prophylaxis is recommended in subjects who are chronically immobilized either at home or at a nursing home.[1]

Long Travel

[1]

 
 
Does the patient has any of the following that increase the risk of VTE?
Prior VTE episode
Recent trauma
Recent surgery
Active cancer
Advanced age
Immobility
Severe obesity
Estrogen intake
Thrombophilia
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Yes
 
No
 
 
 
 
 
 
 
 
 
 
 
 
Frequent ambulation
Calf muscle exercise
To sit in an aisle seat
Graduated compression stockings below the knee (pressure: 15-30 mmHg)
No pharmacological VTE prophylaxis
 
No preventive measures are required
 

Asymptomatic Thrombophilia

VTE prophylaxis is not recommended for subjects with asymptomatic thrombophilia. [1]

VTE Prevention in Non Orthopedic Patients

VTE Prevention in Orthopedic Patients

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Kahn SR, Lim W, Dunn AS, Cushman M, Dentali F, Akl EA; et al. (2012). "Prevention of VTE in nonsurgical patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines". Chest. 141 (2 Suppl): e195S–226S. doi:10.1378/chest.11-2296. PMC 3278052. PMID 22315261.