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(/* Medical Therapy Based on the Drug Adapted from Lancet. 2008;371(9609):329–339. {{cite journal|last1=Bjornson|first1=Candice L|last2=Johnson|first2=David W|title=Croup|journal=The Lancet|volume=371|issue=9609|year=2008|pages=329–339|issn=01406736...)
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! style="height: 30px; line-height: 30px; background: #4479BA; border: 0px; font-size: 100%; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5);" align=center | {{fontcolor|#FFF|Heliox}}
! style="height: 30px; line-height: 30px; background: #4479BA; border: 0px; font-size: 100%; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5);" align=center | {{fontcolor|#FFF|Heliox}}
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| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ There is a short-term benefit of heliox inhalation in children with moderate to severe croup.<ref>{{Cite journal
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ There is no sufficient data that recommends the general use of heliox in patients with croup.<ref name="WeberChudnofsky2001">{{cite journal|last1=Weber|first1=J. E.|last2=Chudnofsky|first2=C. R.|last3=Younger|first3=J. G.|last4=Larkin|first4=G. L.|last5=Boczar|first5=M.|last6=Wilkerson|first6=M. D.|last7=Zuriekat|first7=G. Y.|last8=Nolan|first8=B.|last9=Eicke|first9=D. M.|title=A Randomized Comparison of Helium-Oxygen Mixture (Heliox) and Racemic Epinephrine for the Treatment of Moderate to Severe Croup|journal=PEDIATRICS|volume=107|issue=6|year=2001|pages=e96–e96|issn=0031-4005|doi=10.1542/peds.107.6.e96}}</ref><ref name="BeckmannBrueggemann2000">{{cite journal|last1=Beckmann|first1=Kathleen R.|last2=Brueggemann|first2=William Martin|title=HELIOX TREATMENT OF SEVERE CROUP|journal=The American Journal of Emergency Medicine|volume=18|issue=6|year=2000|pages=735–736|issn=07356757|doi=10.1016/S0735-6757(00)90309-7}}</ref><ref name="GuptaCheifetz2005">{{cite journal|last1=Gupta|first1=Vineet K.|last2=Cheifetz|first2=Ira M.|title=Heliox administration in the pediatric intensive care unit: An evidence-based review|journal=Pediatric Critical Care Medicine|volume=6|issue=2|year=2005|pages=204–211|issn=1529-7535|doi=10.1097/01.PCC.0000154946.62733.94}}</ref>
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| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ Some studies have shown a short-term benefit of heliox inhalation in children with moderate to severe croup.<ref>{{Cite journal
  | author = [[Irene Moraa]], [[Nancy Sturman]], [[Treasure McGuire]] & [[Mieke L. van Driel]]
  | author = [[Irene Moraa]], [[Nancy Sturman]], [[Treasure McGuire]] & [[Mieke L. van Driel]]
  | title = Heliox for croup in children
  | title = Heliox for croup in children
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  | doi = 10.1002/14651858.CD006822.pub4
  | doi = 10.1002/14651858.CD006822.pub4
  | pmid = 24318607
  | pmid = 24318607
}}</ref>
}}</ref><ref>{{Cite journal | author = [[Sarah Kline-Krammes]], [[Christina Reed]], [[John S. Jr Giuliano]], [[Hamilton P. Schwartz]], [[Michael Forbes]], [[John Pope]], [[James Besunder]], [[Michael D. Gothard]], [[Kerry Russell]] & [[Michael T. Bigham]] | title = Heliox in children with croup: a strategy to hasten improvement | journal = [[Air medical journal]] | volume = 31 | issue = 3 | pages = 131–137 | year = 2012 | month = May-June | doi = 10.1016/j.amj.2011.08.004 | pmid = 22541348 }}</ref>
<ref>{{Cite journal | author = [[Sarah Kline-Krammes]], [[Christina Reed]], [[John S. Jr Giuliano]], [[Hamilton P. Schwartz]], [[Michael Forbes]], [[John Pope]], [[James Besunder]], [[Michael D. Gothard]], [[Kerry Russell]] & [[Michael T. Bigham]] | title = Heliox in children with croup: a strategy to hasten improvement | journal = [[Air medical journal]] | volume = 31 | issue = 3 | pages = 131–137 | year = 2012 | month = May-June | doi = 10.1016/j.amj.2011.08.004 | pmid = 22541348 }}</ref>


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Revision as of 14:02, 22 May 2014

SAMPLE

▸ Click on the following categories to expand treatment regimens.

Title

  ▸  Subtitle

  ▸  Subtitle


Table 1
Preferred Regimen
PLUS
Alternative Regimen
Table 2
Preferred Regimen
PLUS
Alternative Regimen

Medical Therapy Based on the Drug Adapted from Lancet. 2008;371(9609):329–339. [1]

▸ Click on the following categories to expand treatment regimens.

Croup Medical Therapy

  ▸  Glucocorticoids

  ▸  Epinephrine

  ▸  Oxygen

  ▸  Mist Therapy

  ▸  Antibiotics

  ▸  Heliox

Glucocorticoids
Mild to Moderate Croup
Dexamethasone 0.60 mg/kg PO/IM/IV, single dose (max. 10 mg)
OR
Budesonide 2mg nebulized
Severe Croup
Dexamethasone 0.60 mg/kg IM/IV, single dose
OR
Budesonide 2mg nebulized
Epinephrine
Mild Croup
There are no indications of nebulized epinephrine for Mild Croup
Moderate to Severe Croup
Nebulized racemic epinephrine (2.25%) 0.05 mL/kg (max. 0.5mL) in 3mL of normal saline for 15 min
OR
Nebulized L-epinephrine 0.5mL/kg (max 5mL) for 15 min
Repeat as needed
Oxygen
▸ Humidified oxygen should be given to patients with hypoxia or severe respiratory distress
Mist Therapy
Antibiotics
Antibiotic are not indicated to treat viral croup
Antibiotics are use for complications, such as bacterial tracheitis or epiglottitis
Heliox
▸ There is no sufficient data that recommends the general use of heliox in patients with croup.[2][3][4]
▸ Some studies have shown a short-term benefit of heliox inhalation in children with moderate to severe croup.[5][6]

Medical Therapy Based on the Severity Adapted from Pediatric Pulmonology 49:421–429 (2014) [7]

▸ Click on the following categories to expand treatment regimens.

Croup Medical Therapy

  ▸  Mild

  ▸  Moderate

  ▸  Severe

Mild
Dexamethasone 0.60 mg/kg PO single dose (max. 10 mg)
OR
Budesonide 2mg nebulized
Moderate
Nebulized racemic epinephrine (2.25%) 0.05 mL/kg (max. 0.5mL) in 3mL of normal saline for 15 min
OR
Nebulized L-epinephrine 0.5mL/kg (max 5mL) for 15 min
Repeat as needed
PLUS
Dexamethasone 0.60 mg/kg PO/IM single dose (max. 10 mg)
OR
Budesonide 2mg nebulized
Severe
Nebulized racemic epinephrine (2.25%) 0.05 mL/kg (max. 0.5mL) in 3mL of normal saline for 15 min
OR
Nebulized L-epinephrine 0.5mL/kg (max 5mL) for 15 min
Repeat as needed
PLUS
Dexamethasone 0.60 mg/kg IM/IV single dose (max. 10 mg)
AND
▸ Hospital admission
  1. Bjornson, Candice L; Johnson, David W (2008). "Croup". The Lancet. 371 (9609): 329–339. doi:10.1016/S0140-6736(08)60170-1. ISSN 0140-6736.
  2. Weber, J. E.; Chudnofsky, C. R.; Younger, J. G.; Larkin, G. L.; Boczar, M.; Wilkerson, M. D.; Zuriekat, G. Y.; Nolan, B.; Eicke, D. M. (2001). "A Randomized Comparison of Helium-Oxygen Mixture (Heliox) and Racemic Epinephrine for the Treatment of Moderate to Severe Croup". PEDIATRICS. 107 (6): e96–e96. doi:10.1542/peds.107.6.e96. ISSN 0031-4005.
  3. Beckmann, Kathleen R.; Brueggemann, William Martin (2000). "HELIOX TREATMENT OF SEVERE CROUP". The American Journal of Emergency Medicine. 18 (6): 735–736. doi:10.1016/S0735-6757(00)90309-7. ISSN 0735-6757.
  4. Gupta, Vineet K.; Cheifetz, Ira M. (2005). "Heliox administration in the pediatric intensive care unit: An evidence-based review". Pediatric Critical Care Medicine. 6 (2): 204–211. doi:10.1097/01.PCC.0000154946.62733.94. ISSN 1529-7535.
  5. Irene Moraa, Nancy Sturman, Treasure McGuire & Mieke L. van Driel (2013). "Heliox for croup in children". The Cochrane database of systematic reviews. 12: CD006822. doi:10.1002/14651858.CD006822.pub4. PMID 24318607.
  6. Sarah Kline-Krammes, Christina Reed, John S. Jr Giuliano, Hamilton P. Schwartz, Michael Forbes, John Pope, James Besunder, Michael D. Gothard, Kerry Russell & Michael T. Bigham (2012). "Heliox in children with croup: a strategy to hasten improvement". Air medical journal. 31 (3): 131–137. doi:10.1016/j.amj.2011.08.004. PMID 22541348. Unknown parameter |month= ignored (help)
  7. Petrocheilou, Argyri; Tanou, Kalliopi; Kalampouka, Efthimia; Malakasioti, Georgia; Giannios, Christos; Kaditis, Athanasios G. (2014). "Viral croup: Diagnosis and a treatment algorithm". Pediatric Pulmonology. 49 (5): 421–429. doi:10.1002/ppul.22993. ISSN 8755-6863.