Creutzfeldt-Jakob disease MRI: Difference between revisions
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==Overview== | ==Overview== | ||
MRI findings in CJD include high signal abnormalities in [[caudate nucleus]] and/or [[putamen]] on diffusion-weighted imaging (DWI) or fluid attenuated inversion recovery (FLAIR). | MRI findings in CJD include high signal abnormalities in [[caudate nucleus]] and/or [[putamen]] on diffusion-weighted imaging (DWI) or fluid attenuated inversion recovery (FLAIR).<ref name="www.cdc.gov">{{Cite web | last = | first = | title = http://www.cdc.gov/ncidod/dvrd/cjd/diagnostic_criteria.html | url = http://www.cdc.gov/ncidod/dvrd/cjd/diagnostic_criteria.html | publisher = | date = | accessdate = 17 February 2014 }}</ref> | ||
== MRI== | == MRI== | ||
* MRI often shows high signal intensity in the [[caudate nucleus]] and [[putamen]] bilaterally on T2-weighted images. | * MRI often shows high signal intensity in the [[caudate nucleus]] and [[putamen]] bilaterally on T2-weighted images. |
Revision as of 03:09, 17 February 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
MRI findings in CJD include high signal abnormalities in caudate nucleus and/or putamen on diffusion-weighted imaging (DWI) or fluid attenuated inversion recovery (FLAIR).[1]
MRI
- MRI often shows high signal intensity in the caudate nucleus and putamen bilaterally on T2-weighted images.
- Diffusion Weighted Imaging (DWI) images are the most sensitive. In about 24% of cases, DWI showed only cortical hyperintensity, cortical and subcortical abnormalities were shown in 68% of cases and in 5%, only subcortical anomalies were present.[2]
- The involvement of the thalamus can be found in sCJD and is even stronger and constant in vCJD.[3]
- An abnormal signal in the posterior thalami on T2- and diffusion-weighted images and fluid-attenuated inversion recovery sequences on brain magnetic resonance imaging (MRI); in the appropriate clinical context, this signal is highly specific for vCJD.
References
- ↑ "http://www.cdc.gov/ncidod/dvrd/cjd/diagnostic_criteria.html". Retrieved 17 February 2014. External link in
|title=
(help) - ↑ Young, Geoffrey S. (June–July 2005). "Diffusion-Weighted and Fluid-Attenuated Inversion Recovery Imaging in Creutzfeldt-Jakob Disease: High Sensitivity and Specificity for Diagnosis". American Journal of Neuroradiology. American Society of Neuroradiology. 26: 1551–1562. Retrieved 2007-10-30. Unknown parameter
|coauthors=
ignored (help) - ↑ Tschampa, Henriette J. (May 2003). "Thalamic Involvement in Sporadic Creutzfeldt-Jakob Disease: A Diffusion-Weighted MR Imaging Study". American Journal of Neuroradiology. American Society of Neuroradiology. 24: 908–915. Retrieved 2007-10-30. Unknown parameter
|coauthors=
ignored (help)