Lisinopril overdosage: Difference between revisions

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==Overdosage==


 
Following a single oral dose of 20 g/kg no lethality occurred in rats, and death occurred in one of 20 mice receiving the same dose. The most likely manifestation of overdosage would be [[hypotension]], for which the usual treatment would be intravenous infusion of normal saline solution.
<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = LISINOPRIL (LISINOPRIL) TABLET [LEK PHARMACEUTICALS] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=27ccb2f4-abf8-4825-9b05-0bb367b4ac07 | publisher =  | date =  | accessdate = }}</ref>
Lisinopril can be removed by [[hemodialysis]].<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = LISINOPRIL (LISINOPRIL) TABLET [LEK PHARMACEUTICALS] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=27ccb2f4-abf8-4825-9b05-0bb367b4ac07 | publisher =  | date =  | accessdate = }}</ref>


==References==
==References==

Revision as of 21:41, 13 February 2014


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2], Amr Marawan, M.D. [3]

Lisinopril

Lisinopril and Hydrochlorothiazide tablet

Overview

Lisinopril tablet is an angiontensin converting enzyme inhibitor drug that is FDA approved for the treatment of hypertension, heart failure, left ventricular dysfunction after myocardial infarction, diabetic nephropathy. Adverse reactions include hypotension, rash, hyperkalemia, disorder of taste, cough. hypotension, rash, hyperkalemia, disorder of taste, cough.

Category

Antihypertensive Agents, Angiotensin Converting Enzyme Inhibitors. Editor-In-Chief: C. Michael Gibson, M.S., M.D. [4]; Associate Editor(s)-in-Chief: Amr Marawan, M.D. [5]

Overdosage

Following a single oral dose of 20 g/kg no lethality occurred in rats, and death occurred in one of 20 mice receiving the same dose. The most likely manifestation of overdosage would be hypotension, for which the usual treatment would be intravenous infusion of normal saline solution. Lisinopril can be removed by hemodialysis.[1]

References

  1. "LISINOPRIL (LISINOPRIL) TABLET [LEK PHARMACEUTICALS]".

Adapted from the FDA Package Insert.