Valacyclovir overdosage: Difference between revisions
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Caution should be exercised to prevent inadvertent overdose [see Use in Specific Populations (8.5, 8.6)]. Precipitation of acyclovir in renal tubules may occur when the solubility (2.5 mg/mL) is exceeded in the intratubular fluid. In the event of [[acute renal failure]] and [[anuria]], the patient may benefit from [[hemodialysis]] until renal function is restored [see Dosage and Administration (2.4)].<ref>{{Cite web | last = | first =|title = http://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020487s014lbl.pdf | url =http://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020487s014lbl.pdf | publisher = |date = | accessdate = }}</ref> | Caution should be exercised to prevent inadvertent overdose [see Use in Specific Populations (8.5, 8.6)]. Precipitation of acyclovir in renal tubules may occur when the solubility (2.5 mg/mL) is exceeded in the intratubular fluid. In the event of [[acute renal failure]] and [[anuria]], the patient may benefit from [[hemodialysis]] until renal function is restored [see Dosage and Administration (2.4)].<ref>{{Cite web | last = | first =|title = http://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020487s014lbl.pdf | url =http://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020487s014lbl.pdf | publisher = |date = | accessdate = }}</ref> | ||
==References== | ==References== | ||
Latest revision as of 23:24, 2 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]
Overdosage
Caution should be exercised to prevent inadvertent overdose [see Use in Specific Populations (8.5, 8.6)]. Precipitation of acyclovir in renal tubules may occur when the solubility (2.5 mg/mL) is exceeded in the intratubular fluid. In the event of acute renal failure and anuria, the patient may benefit from hemodialysis until renal function is restored [see Dosage and Administration (2.4)].[1]
References
- ↑ "http://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020487s014lbl.pdf" (PDF). External link in
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Adapted from the FDA Package Insert.