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'''For patient information page click [[{{PAGENAME}} (patient information)|here]]'''
'''For patient information page click [[{{PAGENAME}} (patient information)|here]]'''
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{{CMG}}; '''Associate Editor-In-Chief:''' {{CZ}}


 
{{SK}} EF
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{{CMG}}
 
'''Associate Editor-In-Chief:''' {{CZ}}
 
==Overview==
==Overview==
'''Eosinophilic fasciitis''' (pronounced {{IPA|/ˌi.ə.sɪn.əˈfiˌlɪk ˌfæ.ʃiˈɑɪ̯.tɪs/}}), or '''EF''', is a form of [[fasciitis]]. It is distinguished from [[scleroderma]] primarily because the affected area is the [[fascia]], not the [[dermis]] as in [[scleroderma]]. Also, unlike scleroderma, [[Raynaud's phenomenon]] and [[telangiectasia]] are not observed.
'''Eosinophilic fasciitis''' (pronounced {{IPA|/ˌi.ə.sɪn.əˈfiˌlɪk ˌfæ.ʃiˈɑɪ̯.tɪs/}}), or '''EF''', is a form of [[fasciitis]]. It is distinguished from [[scleroderma]] primarily because the affected area is the [[fascia]], not the [[dermis]] as in [[scleroderma]]. Also, unlike scleroderma, [[Raynaud's phenomenon]] and [[telangiectasia]] are not observed.


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It is more common in men than in women.<ref name="pmid15510903">{{cite journal |author=Wojas-Pelc A, Wielowieyska-Szybińska D, Lipko-Godlewska S |title=[Eosinophilic fasciitis--current database] |language=Polish |journal=Pol. Merkur. Lekarski |volume=16 |issue=96 |pages=585-8 |year=2004 |pmid=15510903 |doi=}}</ref> Several cases have been reported after strenuous [[exercise]].
It is more common in men than in women.<ref name="pmid15510903">{{cite journal |author=Wojas-Pelc A, Wielowieyska-Szybińska D, Lipko-Godlewska S |title=[Eosinophilic fasciitis--current database] |language=Polish |journal=Pol. Merkur. Lekarski |volume=16 |issue=96 |pages=585-8 |year=2004 |pmid=15510903 |doi=}}</ref> Several cases have been reported after strenuous [[exercise]].
==Differential Diagnosis of Eosinophilic fasciitis==
{|style="width:80%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Chemical / poisoning'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Dermatologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Environmental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Genetic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Iatrogenic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal / Ortho'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Neurologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Nutritional / Metabolic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Oncologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Opthalmologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Overdose / Toxicity'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Psychiatric'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Pulmonary'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Renal / Electrolyte'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Rheum / Immune / Allergy'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Trauma'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Miscellaneous'''
|bgcolor="Beige"| No underlying causes
|-
|}


==Treatment==
==Treatment==
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Common treatments include [[corticosteroid]]s<ref name="pmid16902285">{{cite journal |author=Antic M, Lautenschlager S, Itin PH |title=Eosinophilic fasciitis 30 years after - what do we really know? Report of 11 patients and review of the literature |journal=Dermatology (Basel) |volume=213 |issue=2 |pages=93-101 |year=2006 |pmid=16902285 |doi=10.1159/000093847}}</ref> such as [[prednisone]], though other medications such as [[hydroxychloroquine]]<ref name="pmid3232080">{{cite journal |author=Lakhanpal S, Ginsburg WW, Michet CJ, Doyle JA, Moore SB |title=Eosinophilic fasciitis: clinical spectrum and therapeutic response in 52 cases |journal=Semin. Arthritis Rheum. |volume=17 |issue=4 |pages=221-31 |year=1988 |pmid=3232080 |doi=}}</ref> have also been used.
Common treatments include [[corticosteroid]]s<ref name="pmid16902285">{{cite journal |author=Antic M, Lautenschlager S, Itin PH |title=Eosinophilic fasciitis 30 years after - what do we really know? Report of 11 patients and review of the literature |journal=Dermatology (Basel) |volume=213 |issue=2 |pages=93-101 |year=2006 |pmid=16902285 |doi=10.1159/000093847}}</ref> such as [[prednisone]], though other medications such as [[hydroxychloroquine]]<ref name="pmid3232080">{{cite journal |author=Lakhanpal S, Ginsburg WW, Michet CJ, Doyle JA, Moore SB |title=Eosinophilic fasciitis: clinical spectrum and therapeutic response in 52 cases |journal=Semin. Arthritis Rheum. |volume=17 |issue=4 |pages=221-31 |year=1988 |pmid=3232080 |doi=}}</ref> have also been used.


==See also==
==Related Chapters==
* [[eosinophilia]]
* [[Eosinophilia]]


==References==
==References==
{{reflist|2}}
{{reflist|2}}
==External links==
* [http://www.merck.com/mrkshared/mmanual/section5/chapter50/50h.jsp Merck Manual]
* [http://dermatlas.med.jhmi.edu/derm/result.cfm?Diagnosis=1973850164 DermAtlas]


{{Diseases of the musculoskeletal system and connective tissue}}
{{Diseases of the musculoskeletal system and connective tissue}}


[[Category:Autoimmune diseases]]
[[Category:Autoimmune diseases]]
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[[Category:Inflammations|Fasciitis, eosinophilic]]
[[Category:Inflammations|Fasciitis, eosinophilic]]
[[Category:Rheumatology]]
[[Category:Rheumatology]]


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Revision as of 19:12, 14 November 2012

For patient information page click here

Eosinophilic fasciitis
ICD-10 M35.4
ICD-9 728.89
OMIM 226350
DiseasesDB 29427

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Synonyms and keywords: EF

Overview

Eosinophilic fasciitis (pronounced Template:IPA), or EF, is a form of fasciitis. It is distinguished from scleroderma primarily because the affected area is the fascia, not the dermis as in scleroderma. Also, unlike scleroderma, Raynaud's phenomenon and telangiectasia are not observed.

It was first described in 1975,[1] and it is not yet known whether it is actually a distinct condition or just a different presentation. However, it remains used for diagnostic purposes.

It is more common in men than in women.[2] Several cases have been reported after strenuous exercise.

Treatment

Common treatments include corticosteroids[3] such as prednisone, though other medications such as hydroxychloroquine[4] have also been used.

Related Chapters

References

  1. Shulman LE (1975). "Diffuse fasciitis with eosinophilia: a new syndrome?". Trans. Assoc. Am. Physicians. 88: 70–86. PMID 1224441.
  2. Wojas-Pelc A, Wielowieyska-Szybińska D, Lipko-Godlewska S (2004). "[Eosinophilic fasciitis--current database]". Pol. Merkur. Lekarski (in Polish). 16 (96): 585–8. PMID 15510903.
  3. Antic M, Lautenschlager S, Itin PH (2006). "Eosinophilic fasciitis 30 years after - what do we really know? Report of 11 patients and review of the literature". Dermatology (Basel). 213 (2): 93–101. doi:10.1159/000093847. PMID 16902285.
  4. Lakhanpal S, Ginsburg WW, Michet CJ, Doyle JA, Moore SB (1988). "Eosinophilic fasciitis: clinical spectrum and therapeutic response in 52 cases". Semin. Arthritis Rheum. 17 (4): 221–31. PMID 3232080.

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