Testicular cancer pathophysiology: Difference between revisions

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Revision as of 16:23, 18 September 2012

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Testicular cancer Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Testicular cancer from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT

MRI

Ultrasound

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Biopsy

Treatment

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Primary Prevention

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Cost-Effectiveness of Therapy

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Overview

Pathophysiology

Although testicular cancer can be derived from any cell type found in the testicles, more than 95% of testicular cancers are germ cell tumors. Most of the remaining 5% derive from Leydig cells or Sertoli cells. Thus, the focus of diagnosis is on determining which germ cell tumor is present. Correct diagnosis is necessary to ensure the most effective and least harmful treatment. To some extent, this can be done via blood tests for tumor markers, but differential diagnosis requires examination of the histology of a specimen by a pathologist.

Microscopic pathology

After removal, a testicular tumor is classified by a pathologist according to its histology.

Germ cell tumors of the testis, by frequency

Also: Intratubular germ cell neoplasms (the in-situ stage of germ cell tumors)

Non-germ cell tumors of the testis

Secondary tumors of the testis

References


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