Erythromycin breath test: Difference between revisions

Jump to navigation Jump to search
m (Bot: Automated text replacement (-{{SIB}} + & -{{EJ}} + & -{{EH}} + & -{{Editor Join}} + & -{{Editor Help}} +))
m (Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}}))
 
Line 13: Line 13:
== References ==
== References ==
<div class="references-small">
<div class="references-small">
<references />
{{reflist|2}}
</div>
</div>



Latest revision as of 17:11, 4 September 2012

WikiDoc Resources for Erythromycin breath test

Articles

Most recent articles on Erythromycin breath test

Most cited articles on Erythromycin breath test

Review articles on Erythromycin breath test

Articles on Erythromycin breath test in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Erythromycin breath test

Images of Erythromycin breath test

Photos of Erythromycin breath test

Podcasts & MP3s on Erythromycin breath test

Videos on Erythromycin breath test

Evidence Based Medicine

Cochrane Collaboration on Erythromycin breath test

Bandolier on Erythromycin breath test

TRIP on Erythromycin breath test

Clinical Trials

Ongoing Trials on Erythromycin breath test at Clinical Trials.gov

Trial results on Erythromycin breath test

Clinical Trials on Erythromycin breath test at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Erythromycin breath test

NICE Guidance on Erythromycin breath test

NHS PRODIGY Guidance

FDA on Erythromycin breath test

CDC on Erythromycin breath test

Books

Books on Erythromycin breath test

News

Erythromycin breath test in the news

Be alerted to news on Erythromycin breath test

News trends on Erythromycin breath test

Commentary

Blogs on Erythromycin breath test

Definitions

Definitions of Erythromycin breath test

Patient Resources / Community

Patient resources on Erythromycin breath test

Discussion groups on Erythromycin breath test

Patient Handouts on Erythromycin breath test

Directions to Hospitals Treating Erythromycin breath test

Risk calculators and risk factors for Erythromycin breath test

Healthcare Provider Resources

Symptoms of Erythromycin breath test

Causes & Risk Factors for Erythromycin breath test

Diagnostic studies for Erythromycin breath test

Treatment of Erythromycin breath test

Continuing Medical Education (CME)

CME Programs on Erythromycin breath test

International

Erythromycin breath test en Espanol

Erythromycin breath test en Francais

Business

Erythromycin breath test in the Marketplace

Patents on Erythromycin breath test

Experimental / Informatics

List of terms related to Erythromycin breath test

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3]


The erythromycin breath test (ERMBT) is a method used to measure metabolism (oxidation and elimination from the system) by a part of the cytochrome P450 system. Erythromycin is tagged with carbon-14 and given as an intravenous injection then in 20 minutes the subject blows up a balloon and the carbon dioxide exhaled that is tagged with carbon-14 shows the activity of the CYP3A4 isoenzyme on the erythromycin. Therefore, this activity can predict how other drugs that are metabolized by the CYP3A4 part of the cytochrome P450 system will be acted upon by a particular person.[1]

This is important because it allows doctors to determine or predict an individual’s drug treatment outcome. Will a patient develop serious or fatal side effects from a certain drug? Which foods and drugs should not be taken together? With this and other tests a physician may determine treatment outcomes in advance or study the effects of new drugs.[2]

Some patients have a congenital inability to synthesize certain enzymes, so drugs may build up to toxic levels in their system or other drugs and foods a patient is taking may consume all of their ability to metabolize certain foods and drugs. An example is: when a person taking a cholesterol-lowering Statin drug then drinking grapefruit juice, they may have a poor treatment outcome (Adverse drug reaction) and sustain liver damage or kidney failure due to drug induced Rhabdomyolysis[3](the breaking up of muscle tissue).

References

  1. [1]
  2. PMID 15544435
  3. [2]

Template:WH Template:WS