Clopidogrel dosing and role of genetics: ELEVATE-TIMI 56 trial: Difference between revisions

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The results of the '''ELEVATE-TIMI 56 trial''' were recently presented in [[AHA]] 2011 held at Orlando, Florida.  
The results of the '''ELEVATE-TIMI 56 trial''' were recently presented in [[AHA]] 2011 held at Orlando, Florida.  


<ref name="pmid22088980">{{cite journal| author=Mega JL, Hochholzer W, Frelinger AL, Kluk MJ, Angiolillo DJ, Kereiakes DJ et al.| title=Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease. | journal=JAMA | year= 2011 | volume= 306 | issue= 20 | pages= 2221-8 | pmid=22088980 | doi=10.1001/jama.2011.1703 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22088980  }} </ref>==ELEVATE-TIMI 56 trial ==
==ELEVATE-TIMI 56 trial <ref name="pmid22088980">{{cite journal| author=Mega JL, Hochholzer W, Frelinger AL, Kluk MJ, Angiolillo DJ, Kereiakes DJ et al.| title=Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease. | journal=JAMA | year= 2011 | volume= 306 | issue= 20 | pages= 2221-8 | pmid=22088980 | doi=10.1001/jama.2011.1703 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22088980  }} </ref> ==


* '''Hypothesis''' -  
* '''Hypothesis''' -  

Revision as of 14:45, 25 November 2011

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]

Overview

The results of the ELEVATE-TIMI 56 trial were recently presented in AHA 2011 held at Orlando, Florida.

ELEVATE-TIMI 56 trial [1]

  • Hypothesis -
  • Study design
    • Patient population
      • Multicenter, randomized, double-blind trial
      • Duration of study - 1 years
      • Intervention -
      • Primary end point -
  • Limitations
  • Results -
  • Conclusions

References

  1. Mega JL, Hochholzer W, Frelinger AL, Kluk MJ, Angiolillo DJ, Kereiakes DJ; et al. (2011). "Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease". JAMA. 306 (20): 2221–8. doi:10.1001/jama.2011.1703. PMID 22088980.


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