Cardiac disease in pregnancy and repaired congenital heart disease: Difference between revisions
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{{Pregnancy and heart disease}} | {{Pregnancy and heart disease}} | ||
{{CMG}}; '''Associate Editor-In-Chief:''' {{AC}} | {{CMG}}; '''Associate Editor-In-Chief:''' {{AC}}; ‘’’Assistant Editor-In Chief:’’’ Ara Tachjian [ara_tt@yahoo.com]] | ||
==Overview== | |||
Most of the patients who undergo surgery for congenital heart disease repair will still have some residua of the defect. Therefore, these should be carefully evaluated prior to pregnancy planning. | |||
==Tetralogy of Fallot== | |||
Individuals with TOF usually present very early in life with cyanosis making it necessary to have a surgical repair. The repair is is almost always done during infancy particularly in developed countries. During the surgery, the pulmonary valve and right ventricular outflow tract are both surgically dilated. This usually leads to pulmonary valve regurgitation as well as right sided arrhythmias. Therefore, subsequent right sided heart failure would be expected. At 20 years after the repair, 10-15% might develop late complications, of which the most important is right sided heart failure. <ref name="pmid15894783">{{cite journal| author=Meijer JM, Pieper PG, Drenthen W, Voors AA, Roos-Hesselink JW, van Dijk AP et al.| title=Pregnancy, fertility, and recurrence risk in corrected tetralogy of Fallot. | journal=Heart | year= 2005 | volume= 91 | issue= 6 | pages= 801-5 | pmid=15894783 | doi=10.1136/hrt.2004.034108 | pmc=PMC1768963 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15894783 }} </ref> <ref name="pmid7688102">{{cite journal| author=Murphy JG, Gersh BJ, Mair DD, Fuster V, McGoon MD, Ilstrup DM et al.| title=Long-term outcome in patients undergoing surgical repair of tetralogy of Fallot. | journal=N Engl J Med | year= 1993 | volume= 329 | issue= 9 | pages= 593-9 | pmid=7688102 | doi=10.1056/NEJM199308263290901 | pmc= | url= }} </ref> <ref name="pmid9350942">{{cite journal| author=Nollert G, Fischlein T, Bouterwek S, Böhmer C, Klinner W, Reichart B| title=Long-term survival in patients with repair of tetralogy of Fallot: 36-year follow-up of 490 survivors of the first year after surgical repair. | journal=J Am Coll Cardiol | year= 1997 | volume= 30 | issue= 5 | pages= 1374-83 | pmid=9350942 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9350942 }} </ref> | |||
==References== | ==References== |
Revision as of 00:19, 15 October 2011
Cardiac disease in pregnancy Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Anjan K. Chakrabarti, M.D. [2]; ‘’’Assistant Editor-In Chief:’’’ Ara Tachjian [ara_tt@yahoo.com]]
Overview
Most of the patients who undergo surgery for congenital heart disease repair will still have some residua of the defect. Therefore, these should be carefully evaluated prior to pregnancy planning.
Tetralogy of Fallot
Individuals with TOF usually present very early in life with cyanosis making it necessary to have a surgical repair. The repair is is almost always done during infancy particularly in developed countries. During the surgery, the pulmonary valve and right ventricular outflow tract are both surgically dilated. This usually leads to pulmonary valve regurgitation as well as right sided arrhythmias. Therefore, subsequent right sided heart failure would be expected. At 20 years after the repair, 10-15% might develop late complications, of which the most important is right sided heart failure. [1] [2] [3]
References
- ↑ Meijer JM, Pieper PG, Drenthen W, Voors AA, Roos-Hesselink JW, van Dijk AP; et al. (2005). "Pregnancy, fertility, and recurrence risk in corrected tetralogy of Fallot". Heart. 91 (6): 801–5. doi:10.1136/hrt.2004.034108. PMC 1768963. PMID 15894783.
- ↑ Murphy JG, Gersh BJ, Mair DD, Fuster V, McGoon MD, Ilstrup DM; et al. (1993). "Long-term outcome in patients undergoing surgical repair of tetralogy of Fallot". N Engl J Med. 329 (9): 593–9. doi:10.1056/NEJM199308263290901. PMID 7688102.
- ↑ Nollert G, Fischlein T, Bouterwek S, Böhmer C, Klinner W, Reichart B (1997). "Long-term survival in patients with repair of tetralogy of Fallot: 36-year follow-up of 490 survivors of the first year after surgical repair". J Am Coll Cardiol. 30 (5): 1374–83. PMID 9350942.