Hypercholesterolemia secondary targets: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
==The Metabolic Syndrome== | ==The Metabolic Syndrome== | ||
The [[metabolic syndrome]] is identified as a secondary target of therapy in the NCEP ATP III guidelines, beyond [[LDL]] cholesterol. The [[metabolic syndrome]] is a constellation of multiple risk factors which are lipid and non-lipid in origin. The basic abnormality associated with the [[metabolic syndrome]] is insulin resistance. | The [[metabolic syndrome]] is identified as a secondary target of therapy in the NCEP ATP III guidelines, beyond [[LDL]] cholesterol. The [[metabolic syndrome]] is a constellation of multiple risk factors which are lipid and non-lipid in origin. The basic metabolic abnormality associated with the [[metabolic syndrome]] is insulin resistance. Two main factors are responsible for the development of insulin resistance which include abdominal obesity and physical inactivity. The definition of the [[metabolic syndrome]] includes: | ||
:'''Clinical Identification of the Metabolic Syndrome''' | |||
:{| class="wikitable" border="1" | |||
|+ | |||
! Risk Factor !! Defining level | |||
|- | |||
| ''Abdominal Obesity'':<br>Men<br>Women || ''Waist Circumference'':<br>>102 cm (>40 in)<br>>88 cm (>35 in) | |||
|- | |||
| ''Triglycerides || ≥ 150 mg/dL | |||
|- | |||
| ''HDL cholesterol''<br>Men<br>Women || <br> <40 mg/dL<br> <50 mg/dL | |||
|- | |||
| ''Blood pressure'' || ≥ 130/≥ 85 mmHg | |||
|- | |||
| ''Fasting glucose'' || ≥ 110 mg/dL | |||
|}<br> | |||
==Non-HDL== | ==Non-HDL== | ||
Revision as of 17:22, 15 September 2011
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-632-7753; Associate Editor(s)-In-Chief: Kashish Goel, M.D.
The Metabolic Syndrome
The metabolic syndrome is identified as a secondary target of therapy in the NCEP ATP III guidelines, beyond LDL cholesterol. The metabolic syndrome is a constellation of multiple risk factors which are lipid and non-lipid in origin. The basic metabolic abnormality associated with the metabolic syndrome is insulin resistance. Two main factors are responsible for the development of insulin resistance which include abdominal obesity and physical inactivity. The definition of the metabolic syndrome includes:
- Clinical Identification of the Metabolic Syndrome
Risk Factor Defining level Abdominal Obesity:
Men
WomenWaist Circumference:
>102 cm (>40 in)
>88 cm (>35 in)Triglycerides ≥ 150 mg/dL HDL cholesterol
Men
Women
<40 mg/dL
<50 mg/dLBlood pressure ≥ 130/≥ 85 mmHg Fasting glucose ≥ 110 mg/dL