Noncompaction cardiomyopathy screening: Difference between revisions
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==Overview== | ==Overview== | ||
Noncompaction cardiomyopathy is an inheritable disease, and if a family member is affected, consideration should be given to screening other family members. Symptoms may be quite variable in different family members. | Noncompaction cardiomyopathy is an inheritable disease, and if a family member is affected, consideration should be given to screening other family members. Symptoms may be quite variable in different family members. Recurrence occurs in about 40% of family members. | ||
At least one genetic abnormality has been identified in the gene that encodes for [[alpha-dystrobrevin]]. This is a [[dystrophin-associated protein]] which has been mapped to [[chromosome 18q12]]. The role of this protein is to preserve the structural integrity of the muscle membrane. | At least one genetic abnormality has been identified in the gene that encodes for [[alpha-dystrobrevin]]. This is a [[dystrophin-associated protein]] which has been mapped to [[chromosome 18q12]]. The role of this protein is to preserve the structural integrity of the muscle membrane. |
Revision as of 14:28, 3 August 2011
Noncompaction Cardiomyopathy Microchapters |
Pathophysiology |
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Differentiating Noncompaction Cardiomyopathy from other Diseases |
Diagnosis |
Treatment |
Noncompaction cardiomyopathy screening On the Web |
Risk calculators and risk factors for Noncompaction cardiomyopathy screening |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Noncompaction cardiomyopathy is an inheritable disease, and if a family member is affected, consideration should be given to screening other family members. Symptoms may be quite variable in different family members. Recurrence occurs in about 40% of family members.
At least one genetic abnormality has been identified in the gene that encodes for alpha-dystrobrevin. This is a dystrophin-associated protein which has been mapped to chromosome 18q12. The role of this protein is to preserve the structural integrity of the muscle membrane.