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A '''glomus tumor''' (glomangioma) is a rare [[benign]] [[neoplasm]], is a specialized arteriovenous anastomosis usually found in the skin of the extremities.  It arises from the [[glomus body]].   
A '''glomus tumor''' (glomangioma) is a rare [[benign]] [[neoplasm]], is a specialized arteriovenous anastomosis usually found in the skin of the extremities.  It arises from the [[glomus body]].   


They are usually solitary and small, and most often are found under the fingernails. They can also be found on the [[tympanic membrane]].
==Presentation==


They are often painful, and the pain is reproduced when the lesion is placed in cold water.
They are usually solitary and small, and can be found under the [[fingernails]].<ref name="pmid17875128">{{cite journal |author=Koç O, Kivrak AS, Paksoy Y |title=Subungual glomus tumour: magnetic resonance imaging findings |journal=Australasian radiology |volume=51 Spec No. |issue= |pages=B107–9 |year=2007 |pmid=17875128 |doi=10.1111/j.1440-1673.2007.01797.x |doi_brokendate=2008-06-22}}</ref> They can also be found on the [[tympanic membrane]].<ref name="pmid11981934">{{cite journal |author=De Candia A, Como G, Passon P, Pedace E, Bazzocchi M |title=Sonographic findings in glomus tympanicum tumor |journal=Journal of clinical ultrasound : JCU |volume=30 |issue=4 |pages=236–40 |year=2002 |pmid=11981934 |doi=10.1002/jcu.10058}}</ref>
 
They are often painful, and the pain is reproduced when the lesion is placed in cold water.
 
These tumors tend to have a bluish discoloration, although a white appearance is also noted. Elevation of the nail bed can occurr
 
==Frequency==
 
United States: The exact incidence of glomus tumors is unknown. The multiple variant is rare, accounting for less than 10% of all cases. The probable misdiagnosis of many of these lesions as hemangiomas or venous malformations also makes an accurate assessment of incidence difficult.
 
==Mortality/Morbidity==
 
The most common adverse effect is pain, which is usually associated with solitary lesions. Multiple tumors are less likely to be painful. In one report, a patient with more than 400 glomus tumors had thrombocytopenia as a result of platelet sequestration (ie, Kasabach-Merritt syndrome). Malignant glomus tumors, or glomangiosarcomas, are extremely rare and usually represent a locally infiltrative malignancy. However, metastases do occur and are usually fatal.
 
==Sex==
 
Solitary glomus tumors, particularly subungual lesions, are more common in females than in males. Multiple lesions are slightly more common in males.
 
==Age==
 
Solitary glomus tumors are more frequent in adults than in others. Multiple glomus tumors develop 10-15 years earlier than single lesions; about one third of the cases of multiple tumors occur in those younger than 20 years. Congenital glomus tumors are rare; they are plaquelike in appearance and are considered a variant of multiple glomus tumors.


==Diagnosis==
==Diagnosis==

Revision as of 02:48, 19 January 2009

Glomus tumor
ICD-O: 8711/0
OMIM 138000
DiseasesDB 30732
eMedicine derm/167 
MeSH D005918

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

Overview

Glomus tumor was also the name formerly used for a tumor now called a paraganglioma.

A glomus tumor (glomangioma) is a rare benign neoplasm, is a specialized arteriovenous anastomosis usually found in the skin of the extremities. It arises from the glomus body.

Presentation

They are usually solitary and small, and can be found under the fingernails.[1] They can also be found on the tympanic membrane.[2]

They are often painful, and the pain is reproduced when the lesion is placed in cold water.

These tumors tend to have a bluish discoloration, although a white appearance is also noted. Elevation of the nail bed can occurr

Frequency

United States: The exact incidence of glomus tumors is unknown. The multiple variant is rare, accounting for less than 10% of all cases. The probable misdiagnosis of many of these lesions as hemangiomas or venous malformations also makes an accurate assessment of incidence difficult.

Mortality/Morbidity

The most common adverse effect is pain, which is usually associated with solitary lesions. Multiple tumors are less likely to be painful. In one report, a patient with more than 400 glomus tumors had thrombocytopenia as a result of platelet sequestration (ie, Kasabach-Merritt syndrome). Malignant glomus tumors, or glomangiosarcomas, are extremely rare and usually represent a locally infiltrative malignancy. However, metastases do occur and are usually fatal.

Sex

Solitary glomus tumors, particularly subungual lesions, are more common in females than in males. Multiple lesions are slightly more common in males.

Age

Solitary glomus tumors are more frequent in adults than in others. Multiple glomus tumors develop 10-15 years earlier than single lesions; about one third of the cases of multiple tumors occur in those younger than 20 years. Congenital glomus tumors are rare; they are plaquelike in appearance and are considered a variant of multiple glomus tumors.

Diagnosis

Physical Examination

Ear Nose and Throat


MRI

(Images courtesy of RadsWiki)

See also

References

External links

Template:Epithelial neoplasms Template:SIB


de:Glomustumor


Template:WikiDoc Sources

  1. Koç O, Kivrak AS, Paksoy Y (2007). "Subungual glomus tumour: magnetic resonance imaging findings". Australasian radiology. 51 Spec No.: B107–9. doi:10.1111/j.1440-1673.2007.01797.x. PMID 17875128. Unknown parameter |doi_brokendate= ignored (help)
  2. De Candia A, Como G, Passon P, Pedace E, Bazzocchi M (2002). "Sonographic findings in glomus tympanicum tumor". Journal of clinical ultrasound : JCU. 30 (4): 236–40. doi:10.1002/jcu.10058. PMID 11981934.
  3. http://www.ghorayeb.com
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