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==Pathophysiology==
==Pathophysiology==
Bornholm disease is a disease caused by one of the [[Coxsackie B virus|group B coxsackie virus]]es and is less often caused by a [[Coxsackie A virus|group A coxsackie virus]] or an [[echovirus]], causing pain in the muscles of the chest that join ribs together.
Bornholm disease is a disease caused by one of the [[Coxsackie B virus|group B coxsackie virus]]es and is less often caused by a [[Coxsackie A virus|group A coxsackie virus]] or an [[echovirus]], causing pain in the muscles of the chest that join ribs together.
== Causes ==
Bornholm disease is often due to either the [[Coxsackie A virus|Coxsackie virus]] or [[echovirus]]. The most prevalent strains include [[Coxsackievirus B]], especially B3 and B4, and [[Coxsackievirus A]], including types 4, 6, 9 and 10. [[Echovirus]] types 1, 6, 8, 9 and 19 have also been implicated in some cases. Generally, Coxsackievirus B virus is more prevalent in regards to respiratory complaints compared to Coxsackievirus A strains. The clinical spectrum varies depending on age groups for the Coxsackievirus A and B strains of the virus. Although severe progression of the disease is rare, it has been associated in particular with the Coxsackievirus B3 virus.


==Treatment==
==Treatment==

Revision as of 06:54, 14 February 2022


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Arooj Naz

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Overview

Bornholm disease or epidemic pleurodynia or epidemic myalgia[1] is a disease caused by the Coxsackie B virus or other viruses[2]. The lining around the lungs is called the pleura. Pleurodynia is a general term for pain from this lining, pain in the chest or upper abdomen when the patient breathes. Epidemic pleurodynia is an infection caused by one of several viruses. This type of infection can cause a similar type of pain as the pain that comes from the lining around the lungs. However, in epidemic pleurodynia, the pain comes from the muscles in the chest that join ribs together. Up until 1949, the underlying cause of the disease was undetermined.

Historical Perspective

Bornholm disease is named after the Danish island Bornholm where early cases occurred.

Pathophysiology

Bornholm disease is a disease caused by one of the group B coxsackie viruses and is less often caused by a group A coxsackie virus or an echovirus, causing pain in the muscles of the chest that join ribs together.

Causes

Bornholm disease is often due to either the Coxsackie virus or echovirus. The most prevalent strains include Coxsackievirus B, especially B3 and B4, and Coxsackievirus A, including types 4, 6, 9 and 10. Echovirus types 1, 6, 8, 9 and 19 have also been implicated in some cases. Generally, Coxsackievirus B virus is more prevalent in regards to respiratory complaints compared to Coxsackievirus A strains. The clinical spectrum varies depending on age groups for the Coxsackievirus A and B strains of the virus. Although severe progression of the disease is rare, it has been associated in particular with the Coxsackievirus B3 virus.

Treatment

Treatment includes the administration of nonsteroidal anti-inflammatory agents or the application of heat to the affected muscles.[3] In healthy people, pleurodynia is a harmless infection that goes away on its own within a few days. To treat the muscle pain, your doctor probably will recommend over-the-counter pain relievers. If necessary narcotic pain medication can be used. Aspirin should not be given to children with pleurodynia because of the risk of Reye's syndrome, a serious reaction causing brain and liver injury in children who take aspirin during certain viral illnesses.

Primary Prevention

The viruses that cause epidemic pleurodynia can spread very easily among young children, who tend to put toys or fingers into their mouth. The disease is most likely to spread in day care centers. The best way to prevent infection is to wash hands thoroughly, especially before meals or after changing a diaper or using the bathroom. There is no vaccine to prevent pleurodynia.

References

  1. HOPKINS JH (1950). "Bornholm disease". Br Med J. 1 (4664): 1230–2. PMC 2038054. PMID 15420445. Unknown parameter |month= ignored (help)
  2. Template:DorlandsDict
  3. http://www.intelihealth.com/IH/ihtPrint/WSIHW000/9339/24698.html?hide=t&k=basePrint#when

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