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==Gastroenterology== | ==Gastroenterology== | ||
===Celiac Disease=== | ===Celiac Disease=== | ||
====Overview==== | ====Overview==== | ||
Celiac disease was first discovered by Dutch pediatricians in late 1940, as a disease caused by gluten. After that, main changes was done in disease pathogenesis, diagnosis and treatment. | Celiac disease is an immune-mediated sensitivity to gluten in genetically suspected individuals that mainly affects the small intestinal mucosa. <ref name="pmid25547088">{{cite journal| author=Freeman HJ| title=Celiac disease: a disorder emerging from antiquity, its evolving classification and risk, and potential new treatment paradigms. | journal=Gut Liver | year= 2015 | volume= 9 | issue= 1 | pages= 28-37 | pmid=25547088 | doi=10.5009/gnl14288 | pmc=4282854 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25547088 }} </ref> | ||
====Historical Perspectives==== | |||
Celiac disease was first discovered by Dutch pediatricians in late 1940, as a disease caused by gluten. After that, main changes was done in realizing the disease pathogenesis, diagnosis and treatment.<ref name="pmid29550590">{{cite journal| author=Murray JA, Frey MR, Oliva-Hemker M| title=Celiac Disease. | journal=Gastroenterology | year= 2018 | volume= 154 | issue= 8 | pages= 2005-2008 | pmid=29550590 | doi=10.1053/j.gastro.2017.12.026 | pmc=6203336 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29550590 }} </ref> | |||
==== | |||
Patients with celiac disease presents at young age with: | Patients with celiac disease presents at young age with: | ||
# GIT symptoms | # GIT symptoms | ||
| Line 9: | Line 11: | ||
# Vitamin def | # Vitamin def | ||
'''Physical Examinations''' | '''Physical Examinations''' | ||
==References== | |||
{{Reflist|2}} | |||
Revision as of 01:14, 11 February 2021
Gastroenterology
Celiac Disease
Overview
Celiac disease is an immune-mediated sensitivity to gluten in genetically suspected individuals that mainly affects the small intestinal mucosa. [1]
Historical Perspectives
Celiac disease was first discovered by Dutch pediatricians in late 1940, as a disease caused by gluten. After that, main changes was done in realizing the disease pathogenesis, diagnosis and treatment.[2]
==
Patients with celiac disease presents at young age with:
- GIT symptoms
- Dermatological symptoms
- Vitamin def
Physical Examinations
References
- ↑ Freeman HJ (2015). "Celiac disease: a disorder emerging from antiquity, its evolving classification and risk, and potential new treatment paradigms". Gut Liver. 9 (1): 28–37. doi:10.5009/gnl14288. PMC 4282854. PMID 25547088.
- ↑ Murray JA, Frey MR, Oliva-Hemker M (2018). "Celiac Disease". Gastroenterology. 154 (8): 2005–2008. doi:10.1053/j.gastro.2017.12.026. PMC 6203336. PMID 29550590.