Cervical cancer classification: Difference between revisions

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Cervical cancer may be classified into many subtypes based on WHO histological classification.
Cervical cancer may be classified into many subtypes based on WHO histological classification.


==Classification==
==Classification ==
Newly revised FIGO staging for cervical cancer, included pathological and imaging findings as well as clinical manifestations.


==References==
FIGO staging of cancer of the cervix uteri (2018)
{| class="wikitable"
!Stage
!Description
|-
|I
|The carcinoma is strictly confined to the cervix (extension to the uterine corpus should be disregarded)
|-
|IA
|Invasive carcinoma that can be diagnosed only by microscopy, with maximum depth of invasion <5 mma
|-
|IA1
|Measured stromal invasion <3 mm in depth
|-
|IA2
|Measured stromal invasion ≥3 mm and <5 mm in depth
|-
|IB
|Invasive carcinoma with measured deepest invasion ≥5 mm (greater than Stage IA), lesion limited to the cervix uterib
|-
|IB1
|Invasive carcinoma ≥5 mm depth of stromal invasion, and <2 cm in greatest dimension
|-
|IB2
|Invasive carcinoma ≥2 cm and <4 cm in greatest dimension
|-
|IB3
|Invasive carcinoma ≥4 cm in greatest dimension
|-
|II
|The carcinoma invades beyond the uterus, but has not extended onto the lower third of the vagina or to the pelvic wall
|-
|IIA
|Involvement limited to the upper two‐thirds of the vagina without parametrial involvement
|-
|IIA1
|Invasive carcinoma <4 cm in greatest dimension
|-
|IIA2
|Invasive carcinoma ≥4 cm in greatest dimension
|-
|IIB
|With parametrial involvement but not up to the pelvic wall
|-
|III
|The carcinoma involves the lower third of the vagina and/or extends to the pelvic wall and/or causes hydronephrosis or nonfunctioning kidney and/or involves pelvic and/or para‐aortic lymph nodesc
|-
|IIIA
|The carcinoma involves the lower third of the vagina, with no extension to the pelvic wall
|-
|IIIB
|Extension to the pelvic wall and/or hydronephrosis or nonfunctioning kidney (unless known to be due to another cause)
|-
|IIIC
|Involvement of pelvic and/or para‐aortic lymph nodes, irrespective of tumor size and extent (with r and p notations)c
|-
|IIIC1
|Pelvic lymph node metastasis only
|-
|IIIC2
|Para‐aortic lymph node metastasis
|-
|IV
|The carcinoma has extended beyond the true pelvis or has involved (biopsy proven) the mucosa of the bladder or rectum. (A bullous edema, as such, does not permit a case to be allotted to Stage IV)
|-
|IVA
|Spread to adjacent pelvic organs
|-
|IVB
|Spread to distant organs
|}
 
==References ==
{{reflist|2}}
{{reflist|2}}



Revision as of 19:56, 8 February 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Cervical cancer may be classified into many subtypes based on WHO histological classification.

Classification

Newly revised FIGO staging for cervical cancer, included pathological and imaging findings as well as clinical manifestations.

FIGO staging of cancer of the cervix uteri (2018)

Stage Description
I The carcinoma is strictly confined to the cervix (extension to the uterine corpus should be disregarded)
IA Invasive carcinoma that can be diagnosed only by microscopy, with maximum depth of invasion <5 mma
IA1 Measured stromal invasion <3 mm in depth
IA2 Measured stromal invasion ≥3 mm and <5 mm in depth
IB Invasive carcinoma with measured deepest invasion ≥5 mm (greater than Stage IA), lesion limited to the cervix uterib
IB1 Invasive carcinoma ≥5 mm depth of stromal invasion, and <2 cm in greatest dimension
IB2 Invasive carcinoma ≥2 cm and <4 cm in greatest dimension
IB3 Invasive carcinoma ≥4 cm in greatest dimension
II The carcinoma invades beyond the uterus, but has not extended onto the lower third of the vagina or to the pelvic wall
IIA Involvement limited to the upper two‐thirds of the vagina without parametrial involvement
IIA1 Invasive carcinoma <4 cm in greatest dimension
IIA2 Invasive carcinoma ≥4 cm in greatest dimension
IIB With parametrial involvement but not up to the pelvic wall
III The carcinoma involves the lower third of the vagina and/or extends to the pelvic wall and/or causes hydronephrosis or nonfunctioning kidney and/or involves pelvic and/or para‐aortic lymph nodesc
IIIA The carcinoma involves the lower third of the vagina, with no extension to the pelvic wall
IIIB Extension to the pelvic wall and/or hydronephrosis or nonfunctioning kidney (unless known to be due to another cause)
IIIC Involvement of pelvic and/or para‐aortic lymph nodes, irrespective of tumor size and extent (with r and p notations)c
IIIC1 Pelvic lymph node metastasis only
IIIC2 Para‐aortic lymph node metastasis
IV The carcinoma has extended beyond the true pelvis or has involved (biopsy proven) the mucosa of the bladder or rectum. (A bullous edema, as such, does not permit a case to be allotted to Stage IV)
IVA Spread to adjacent pelvic organs
IVB Spread to distant organs

References

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