Rhabdomyosarcoma risk factors: Difference between revisions

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The common risk factors in the development of rhabdomyosarcoma are [[Beckwith-Wiedemann syndrome]], [[Li-Fraumeni syndrome]], [[Costello syndrome]], and [[Noonan syndrome]].
The common risk factors in the development of rhabdomyosarcoma are [[Beckwith-Wiedemann syndrome]], [[Li-Fraumeni syndrome]], [[Costello syndrome]], and [[Noonan syndrome]].
==Risk Factors==
==Risk Factors==
*The same as all other childhood cancers, the particular risk factors of rhabdomyosarcoma is not exactly known.
* The same as all other childhood cancers, the particular risk factors of rhabdomyosarcoma is not exactly known.<ref name="pmid6948120">{{cite journal| author=Grufferman S, Wang HH, DeLong ER, Kimm SY, Delzell ES, Falletta JM| title=Environmental factors in the etiology of rhabdomyosarcoma in childhood. | journal=J Natl Cancer Inst | year= 1982 | volume= 68 | issue= 1 | pages= 107-13 | pmid=6948120 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6948120  }} </ref>
* Higher incidence of rhabdomyosarcoma is reported among following individuals:<ref name="pmid2815346">{{cite journal| author=Magnani C, Pastore G, Luzzatto L, Carli M, Lubrano P, Terracini B| title=Risk factors for soft tissue sarcomas in childhood: a case-control study. | journal=Tumori | year= 1989 | volume= 75 | issue= 4 | pages= 396-400 | pmid=2815346 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2815346  }} </ref><ref name="pmid3224086">{{cite journal| author=Hartley AL, Birch JM, McKinney PA, Teare MD, Blair V, Carrette J et al.| title=The Inter-Regional Epidemiological Study of Childhood Cancer (IRESCC): case control study of children with bone and soft tissue sarcomas. | journal=Br J Cancer | year= 1988 | volume= 58 | issue= 6 | pages= 838-42 | pmid=3224086 | doi= | pmc=2246858 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3224086  }} </ref><ref name="pmid19997102">{{cite journal| author=Ognjanovic S, Carozza SE, Chow EJ, Fox EE, Horel S, McLaughlin CC et al.| title=Birth characteristics and the risk of childhood rhabdomyosarcoma based on histological subtype. | journal=Br J Cancer | year= 2010 | volume= 102 | issue= 1 | pages= 227-31 | pmid=19997102 | doi=10.1038/sj.bjc.6605484 | pmc=2813761 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19997102  }} </ref>
** Exposure to radiation in utero
** Low socio-economic situations
** Anti-biotic therapy soon after birth
** In children whose parents took recreational drugs during pregnancy<ref name="pmid8318638">{{cite journal| author=Grufferman S, Schwartz AG, Ruymann FB, Maurer HM| title=Parents' use of cocaine and marijuana and increased risk of rhabdomyosarcoma in their children. | journal=Cancer Causes Control | year= 1993 | volume= 4 | issue= 3 | pages= 217-24 | pmid=8318638 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8318638  }} </ref>
**Accelerated growth in utero
The risk factors for the development of rhabdomyosarcoma are:
The risk factors for the development of rhabdomyosarcoma are:
*[[Beckwith-Wiedemann syndrome]]
*[[Beckwith-Wiedemann syndrome]]

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]

Overview

The common risk factors in the development of rhabdomyosarcoma are Beckwith-Wiedemann syndrome, Li-Fraumeni syndrome, Costello syndrome, and Noonan syndrome.

Risk Factors

  • The same as all other childhood cancers, the particular risk factors of rhabdomyosarcoma is not exactly known.[1]
  • Higher incidence of rhabdomyosarcoma is reported among following individuals:[2][3][4]
    • Exposure to radiation in utero
    • Low socio-economic situations
    • Anti-biotic therapy soon after birth
    • In children whose parents took recreational drugs during pregnancy[5]
    • Accelerated growth in utero

The risk factors for the development of rhabdomyosarcoma are:

References

  1. Grufferman S, Wang HH, DeLong ER, Kimm SY, Delzell ES, Falletta JM (1982). "Environmental factors in the etiology of rhabdomyosarcoma in childhood". J Natl Cancer Inst. 68 (1): 107–13. PMID 6948120.
  2. Magnani C, Pastore G, Luzzatto L, Carli M, Lubrano P, Terracini B (1989). "Risk factors for soft tissue sarcomas in childhood: a case-control study". Tumori. 75 (4): 396–400. PMID 2815346.
  3. Hartley AL, Birch JM, McKinney PA, Teare MD, Blair V, Carrette J; et al. (1988). "The Inter-Regional Epidemiological Study of Childhood Cancer (IRESCC): case control study of children with bone and soft tissue sarcomas". Br J Cancer. 58 (6): 838–42. PMC 2246858. PMID 3224086.
  4. Ognjanovic S, Carozza SE, Chow EJ, Fox EE, Horel S, McLaughlin CC; et al. (2010). "Birth characteristics and the risk of childhood rhabdomyosarcoma based on histological subtype". Br J Cancer. 102 (1): 227–31. doi:10.1038/sj.bjc.6605484. PMC 2813761. PMID 19997102.
  5. Grufferman S, Schwartz AG, Ruymann FB, Maurer HM (1993). "Parents' use of cocaine and marijuana and increased risk of rhabdomyosarcoma in their children". Cancer Causes Control. 4 (3): 217–24. PMID 8318638.

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