Interstitial nephritis epidemiology and demographics: Difference between revisions

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==Overview==
==Overview==
Interstitial nephritis accounts for 10-15% of kidney disease worlwide.
Analgesic-induced nephritis is 5-6 times more common in women.
The elderly have more severe disease and increased risk of permanent damage.
Children exposed to lead poisoning ARE more likely to develop nephritis as young adult.
TIN with uveitis is more common in adolescent female.


==Epidemiology and Demographics==
==Epidemiology and Demographics==
Line 12: Line 21:
*
*
===Prevalence===
===Prevalence===
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
While the definitive diagnosis of AIN needs a kidney biopsy,then determination of  prevalence of AIN are based on retrospective reviews of biopsy registries, with an overall average of 2.8%of the total biopsies. The incidence of AIN increases among biopsies done specifically to evaluate acute renal failure of unknown origin,with an overall average of 13.5%.  
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
*The prevalence of ATIN has increased in recent years, especially in patients aged >65 years. This could be due to an increase in drug-associated ATIN, which would justify early renal biopsy to identify ATIN and reduce the probability of progression to chronic kidney disease. Although, our data are not able to corroborate this fact.
*The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
 
*
===Case-fatality rate/Mortality rate===
*In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
*The case-fatality rate/mortality rate of [disease name] is approximately [number range].
*
===Age===
===Age===
*Patients of all age groups may develop [disease name].
*Patients of all age groups may develop TIN.The elderly have more severe disease and increased risk of permanent damage
*The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
*Children exposed to lead poisoning ARE more likely to develop nephritis as young adult.
*[Disease name] commonly affects individuals younger than/older than [number of years] years of age.
*TIN with uveitis is more common in adolescent female
*[Chronic disease name] is usually first diagnosed among [age group].
*Tubulointerstitial nephritis and uveitis (TINU) syndrome
*[Acute disease name] commonly affects [age group].
===Race===
===Race===
*There is no racial predilection to [disease name].
*There is no racial predilection to TIN; whereas, lead nephropathy is more common in black people owing to socioeconomic factors.
*[Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].
===Gender===
===Gender===
*[Disease name] affects men and women equally.
*Analgesic-induced nephritis is 5-6 times more common in women, attributed to women taking more analgesics than men.
*[Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.
*
===Region===
===Region===
*The majority of [disease name] cases are reported in [geographical region].
* In certain regions, such as the Balkans (ie, Yugoslavia, Bosnia, Croatia, Romania, Bulgaria), where endemic nephropathy is common, interstitial diseases may be more prevalent.
 
*[Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
===Developed Countries===
===Developed Countries===
===Developing Countries===
===Developing Countries===

Revision as of 00:42, 30 June 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohsen Basiri M.D.

Overview

Interstitial nephritis accounts for 10-15% of kidney disease worlwide.

Analgesic-induced nephritis is 5-6 times more common in women.

The elderly have more severe disease and increased risk of permanent damage.

Children exposed to lead poisoning ARE more likely to develop nephritis as young adult.

TIN with uveitis is more common in adolescent female.

Epidemiology and Demographics

Incidence

  • The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
  • In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.

Prevalence

While the definitive diagnosis of AIN needs a kidney biopsy,then determination of prevalence of AIN are based on retrospective reviews of biopsy registries, with an overall average of 2.8%of the total biopsies. The incidence of AIN increases among biopsies done specifically to evaluate acute renal failure of unknown origin,with an overall average of 13.5%.

  • The prevalence of ATIN has increased in recent years, especially in patients aged >65 years. This could be due to an increase in drug-associated ATIN, which would justify early renal biopsy to identify ATIN and reduce the probability of progression to chronic kidney disease. Although, our data are not able to corroborate this fact.

Age

  • Patients of all age groups may develop TIN.The elderly have more severe disease and increased risk of permanent damage
  • Children exposed to lead poisoning ARE more likely to develop nephritis as young adult.
  • TIN with uveitis is more common in adolescent female
  • Tubulointerstitial nephritis and uveitis (TINU) syndrome

Race

  • There is no racial predilection to TIN; whereas, lead nephropathy is more common in black people owing to socioeconomic factors.

Gender

  • Analgesic-induced nephritis is 5-6 times more common in women, attributed to women taking more analgesics than men.

Region

  •  In certain regions, such as the Balkans (ie, Yugoslavia, Bosnia, Croatia, Romania, Bulgaria), where endemic nephropathy is common, interstitial diseases may be more prevalent.

Developed Countries

Developing Countries

References

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