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Parotid stones are the smaller ones, and they are more located within the glands.  
Parotid stones are the smaller ones, and they are more located within the glands.  


Stone formation is more in the submandibular gland.<ref name="pmid3318353" />
Stone formation is 80 to 90 percent in the submandibular gland, 6 to 20 percent in the parotid glands, 1 to 2 percent occur in the sublingual or minor salivary glands .<ref name="pmid3318353" />


Stones occur equally on the right and left sides.
Stones occur equally on the right and left sides.
Most (80 to 90 percent) salivary gland stones occur in the submandibular glands, 6 to 20 percent occur in the parotid glands, and 1 to 2 percent occur in the sublingual or minor salivary glands [1,8,9]. Submandibular stones tend to be larger than stones in other glands and are most often located in the duct. Parotid stones tend to be smaller than submandibular stones, are more often multiple, and 50 percent of the time are located within the gland itself.
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Revision as of 16:20, 29 January 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

The exact pathogenesis of [disease name] is not fully understood.

OR

It is thought that [disease name] is the result of / is mediated by / is produced by / is caused by either [hypothesis 1], [hypothesis 2], or [hypothesis 3].

OR

[Pathogen name] is usually transmitted via the [transmission route] route to the human host.

OR

Following transmission/ingestion, the [pathogen] uses the [entry site] to invade the [cell name] cell.

OR


[Disease or malignancy name] arises from [cell name]s, which are [cell type] cells that are normally involved in [function of cells].

OR

The progression to [disease name] usually involves the [molecular pathway].

OR

The pathophysiology of [disease/malignancy] depends on the histological subtype.

Pathophysiology

Pathogenesis

It is understood that sialolithiasis is the result of calculi obstruction in the salivary glands.

Component of salivary stones include: [1]

  • Calcium phosphate
  • Hydroxyapatite
  • Magnesium
  • Ammonium
  • Potassium

Parotid, submandibular, and sublingual glands and minor salivary glands are prone to the development of stones.

Parotid glands and stensen ducts are located anterior to the external auditory canal.

Submandibular glands and wharton ducts are located beneath the floor of the mouth.

Sublingual glands are located beneath the mucous membrane of the floor of the mouth.

75 percent of sialadenosis cases are single

3 percent of stones are bilateral and most of them are located in parotid glands.

Submandibular stones are the largest ones and are often located in the wharton ducts.

Parotid stones are the smaller ones, and they are more located within the glands.

Stone formation is 80 to 90 percent in the submandibular gland, 6 to 20 percent in the parotid glands, 1 to 2 percent occur in the sublingual or minor salivary glands .[2]

Stones occur equally on the right and left sides.

Most (80 to 90 percent) salivary gland stones occur in the submandibular glands, 6 to 20 percent occur in the parotid glands, and 1 to 2 percent occur in the sublingual or minor salivary glands [1,8,9]. Submandibular stones tend to be larger than stones in other glands and are most often located in the duct. Parotid stones tend to be smaller than submandibular stones, are more often multiple, and 50 percent of the time are located within the gland itself.

  • The pathophysiology of [disease/malignancy] depends on the histological subtype.

Genetics

  • [Disease name] is transmitted in [mode of genetic transmission] pattern.
  • Genes involved in the pathogenesis of [disease name] include [gene1], [gene2], and [gene3].
  • The development of [disease name] is the result of multiple genetic mutations.

Associated Conditions

Gross Pathology

  • On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].

Microscopic Pathology

  • On microscopic histopathological analysis, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].

References

  1. Williams MF (1999). "Sialolithiasis". Otolaryngol. Clin. North Am. 32 (5): 819–34. PMID 10477789.

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