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| | {{#ev:youtube|https://https://www.youtube.com/watch?v=WsmW6I0cmBE|350}}
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| __NOTOC__
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| {{Gallbladder cancer}}
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| {{CMG}}
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| ==Overview==
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| The pathophysiology of gallbladder cancer depends on the histologic subtypes.
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| ==Pathological Findings==
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| ===Squamous cell gallbladder cancer===
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| [[Squamous cell carcinoma|Squamous cell cancers]] develop from the skin-like cells that form the lining of the gallbladder, along with the gland cells.
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| ===Adenosquamous gallbladder cancer===
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| [[Adenosquamous carcinoma|Adenosquamous carcinomas]] are cancers that have both squamous cancer cells and glandular cancer cells.
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| ===Small cell cancer of the gallbladder===
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| [[Small cell carcinoma|Small cell carcinomas]] are also called [[oat cell carcinoma|oat cell carcinomas]]. They are called this because the cancer cells are a distinctive oat shape.
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| ===Gallbladder sarcomas===
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| [[Sarcoma]] is the name for a [[cancer]] that affects the supportive or protecting tissues of the body – also called the connective tissues. Muscles, blood vessels and nerves are all connective tissues. A cancer that begins in the muscle layer of the gallbladder is a sarcoma.
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| Over 90% of cases of gallbladder cancer are [[adenocarcinoma|adenocarcinomas]].
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| [http://www.peir.net Images courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology]
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| <gallery>
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| Image:Gallbladder carcinoma 1.jpg|Gallbladder carcinoma: Gross, natural color, close-up view of liver and gallbladder slice with typical neoplasm invading liver and surround a cavity with mixed type gallstones
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| Image:Gallbladder carcinoma 2.jpg|Gallbladder carcinoma: Gross, natural color close-up view of gallbladder obliterated by white neoplasm with invasion of liver in a sunburst pattern slice of liver and gallbladder (an outstanding example of this rather rare tumor)
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| Image:Gallbladder carcinoma 3.jpg|Gallbladder carcinoma: Gross, natural color shows stones in middle of tumor localization
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| </gallery>
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| <gallery>
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| Image:Gallbladder carcinoma 4.jpg|Gallbladder carcinoma: Gross, natural color slab of liver with gallbladder
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| Image:Gallbladder carcinoma 5.jpg|Gallbladder: Adenocarcinoma, arising from bile ducts
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| Image:Gallbladder carcinoma 6.jpg|Gallbladder carcinoma: Gross, natural color of slice of liver showing attached gallbladder obliterated by tumor and with tumor invading adjacent liver parenchyma like a sunburst (an excellent example)
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| </gallery>
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| ===Microscopic Pathology===
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| <gallery>
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| Image:Gallbladder adenocarcinoma (2) histopathology.jpg|[[Gallbladder adenocarcinoma]] histopathology
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| Image:Gallbladder adenocarcinoma (3) lymphatic invasion histopathology.jpg|[[Gallbladder adenocarcinoma]]: Lymphatic invasion histopathology
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| Image:Gallbladder adenocarcinoma (1) histopathology.jpg|[[Gallbladder adenocarcinoma]]: Incidentally discovered gallbladder cancer ([[adenocarcinoma]]) following a [[cholecystectomy]]. [[H&E stain]]
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| </gallery>
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| ==References==
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| {{reflist|2}}
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| [[Category:Disease]]
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| [[Category:Types of cancer]]
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| [[Category:Gastroenterology]]
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